Journal of Surgical Research
Volume 138, Issue 1 , Pages 22-24 , March 2007

Prognostic Scoring in Patients With Melanoma After Adjuvant Isolated Limb Perfusion

Presented at the 1st Annual Academic Surgical Congress (Association for Academic Surgery), San Diego, CA, February 7–11, 2006.

  • Jumkur S. Nagabhúshan, M.B.B.S., M.S., F.R.C.S.Ed.

      Affiliations

    • Department of Vascular and General Surgery, Gartnavel General Hospital, North Glasgow University Hospitals, Glasgow, UK
    • ,
  • Karen Murphy

      Affiliations

    • Department of Vascular and General Surgery, Gartnavel General Hospital, North Glasgow University Hospitals, Glasgow, UK
    • ,
  • Wilson Angerson, M.B.B.S., M.D.

      Affiliations

    • University Department of Surgery, Glasgow Royal Infirmary, Glasgow, UK
    • ,
  • David B. Kingsmore, M.B.B.S., F.R.C.S.

      Affiliations

    • Department of Vascular and General Surgery, Gartnavel General Hospital, North Glasgow University Hospitals, Glasgow, UK
    • ,
  • Dominic S. Byrne, M.B.B.S., F.R.C.S.

      Affiliations

    • Department of Vascular and General Surgery, Gartnavel General Hospital, North Glasgow University Hospitals, Glasgow, UK
    • ,
  • Allan J. McKay, M.B. Ch.B., M.D., F.R.C.S.

      Affiliations

    • Department of Vascular and General Surgery, Gartnavel General Hospital, North Glasgow University Hospitals, Glasgow, UK
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Surgery, Gartnavel General Hospital, 1053 Great Western Road, Glasgow, G12 0YN, UK.

Received 9 January 2006

References 

  1. Queirolo P, Acquati M, Kirkwood JM, Eggermont AM, Rocca A, Testori A. Update: Current management issues in malignant melanoma. Melanoma Res. 2005;15:319
  2. Matheson J, Summerfield C. In: Social Trends 30. London: The Stationery Office; 2000;p. 121;http://www.statistics.gov.uk
  3. Clark WH, Elder DE, Guerry D. Model predicting survival in stage I melanoma based on tumor progression. J Natl Cancer Inst. 1989;81:1893
  4. Koops HS, Vaglini M, Sucius S, et al. Prophylactic isolated limb perfusion for localized, high-risk limb melanoma: Results of a multicenter randomized phase III trial (European Organization for Research and Treatment of Cancer Malignant Melanoma Cooperative Group Protocol 18832, the World Health Organization Melanoma Program Trial 15, and the North American Perfusion Group Southwest Oncology Group-8593). J Clin Oncol. 1998;16:2906
  5. MacKie RM, Aitchison T, Sirel JM, McLaren K, Watt DC. Prognostic models for subgroups of melanoma patients from the Scottish Melanoma Group database 1979-86, and their subsequent validation. Br J Cancer. 1995;71:173
  6. Margolis DJ, Halpern AC, Rebbeck T, et al. Validation of a melanoma prognostic model. Arch Dermatol. 1998;134:1597
  7. Cochran AJ, Elashoff D, Morton DL, Elashoff R. Individualized prognosis for melanoma patients. Hum Pathol. 2000;31:327
  8. Lingam MK, Byrne DS, Aitchison T, MacKie RM, McKay AJ. A single centre’s 10 year experience with isolated limb perfusion in the treatment of recurrent malignant melanoma of the limb. Eur J Cancer. 1996;32A:1668
  9. Vrouenraets BC, Nieweg OE, Kroon BB. Thirty-five years of isolated limb perfusion for melanoma: Indications and results. Br J Surg. 1996;83:1319
  10. Wieberdink J, Benckhuysen C, Braat RP, van Slooten EA, Olthuis GA. Dosimetry in isolation perfusion of the limbs by assessment of perfused tissue volume and grading of toxic tissue reactions. Eur J Cancer Clin Oncol. 1982;18:905
  11. Lingam MK, McKay AJ, MacKie RM, Aitchison T. Single-centre prospective study of isolated limb perfusion with melphalan in the treatment of subungual malignant melanoma. Br J Surg. 1995;82:1343
  12. Ghussen F, Nagel K, Groth W, Muller JM, Stutzer H. A prospective randomized study of regional extremity perfusion in patients with malignant melanoma. Ann Surg. 1984;200:764

PII: S0022-4804(06)00256-3

doi: 10.1016/j.jss.2006.05.016

Journal of Surgical Research
Volume 138, Issue 1 , Pages 22-24 , March 2007

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