Journal of Surgical Research
Volume 138, Issue 2 , Pages 156-162 , April 2007

Differential Regulation of the Superoxide Dismutase Family in Experimental Aortic Aneurysms and Rat Aortic Explants

Presented at the 38th Annual Meeting of the Association for Academic Surgery, Houston, TX, November 11–13, 2004.

Received 10 July 2006

References 

  1. Ailawadi G, Eliason JL, Upchurch GR. Current concepts in the pathogenesis of abdominal aortic aneurysms. J Vasc Surg. 2003;38:584
  2. McMillan WD, Patterson BK, Keen RR, Pearce WH. In situ localization and quantification of 72 kD type IV collagenase in aneurysmal, occlusive, and normal aorta. J Vasc Surg. 1995;22:295
  3. McMillan WD, Patterson BK, Keen RR, Shively VP, Cipollone M, Pearce WH. In situ localization and quantification of mRNA for 92 kD gelatinase in abdominal aortic aneurysms and its inhibitor in aneurysmal, occlusive, and normal aorta. Arterioscler Thromb Vasc Biol. 1995;14:1139
  4. Thompson RW, Holmes DR, Mertens RA, et al. Production and localization of 92 kD gelatinase in abdominal aortic aneurysms: An elastolytic metalloproteinase expressed by aneurysm infiltrating macrophages. J Clin Invest. 1995;96:318
  5. Tamarina NA, McMillan WD, Shively VP, Pearce WH. Expression of matrix metalloproteinases and their inhibitors in aneurysmal and normal aorta. Surgery. 1997;122:264
  6. Curci JA, Liao S, Huffman MD, Shapiro SD, Thompson RW. Expression and colocalization of macrophage elastase (MMP-12) in abdominal aortic aneurysms. J Clin Invest. 1998;102:1900
  7. Sinha I, Hannawa KK, Eliason JL, et al. Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms. Surgery. 2004;136:176
  8. Freestone T, Turner RJ, Coady A, Higman DJ, Greenhalgh RM, Powell JT. Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol. 1995;15:1145
  9. Pyo R, Lee JK, Shipley M, et al. Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of abdominal aortic aneurysms. J Clin Invest. 2000;105:1641
  10. Longo MG, Xiong W, Greiner TC, Zhao Y, Fiotti N, Baxter TB. Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest. 2002;110:625
  11. Rajogopalan S, Meng XP, Ramasamy S, Harrison DG, Galis ZS. Reactive oxygen species produced by macrophage derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. J Clin Invest. 1996;98:2572
  12. Uemera S, Matsushita H, Li W, et al. Diabetes mellitus enhances vascular matrix metalloproteinase activity: Role of oxidative stress. Circ Res. 2001;1291:
  13. Warner RL, Bless NM, Lewis CS, et al. Time-dependant inhibition of immune complex mediated lung disease by catalase: Relationship to alterations in neutrophil and macrophage metalloproteinase elaboration. Free Radic Biol Med. 2000;29:8
  14. Nelson KK, Melendez JA. Mitochondrial redox control of matrix metalloproteinases. Free Radic Biol Med. 2004;37:768
  15. Yajima N, Masuda M, Miyazaki M, Nakajima N, Chien S, Shyy JY. Oxidative stress is involved in the development of experimental aortic aneurysm: A study of the transcription profile with complimentary DNA microarray. J Vasc Surg. 2002;36:379
  16. Miller FJ, Sharp WJ, Xiang F, Oberley LW, Oberley TD, Weintraub NL. Oxidative stress in human abdominal aortic aneurysms: A potential mediator of aneurysmal remodeling. Arterioscler Thromb Vasc Biol. 2002;22:560
  17. Grigoryants V, Hannawa KK, Pearce CG, et al. Tamoxifen upregulates catalase production, inhibits vessel wall neutrophil infiltration, and attenuates development of abdominal aortic aneurysms. J Vasc Surg. 2005;41:108
  18. Thompson RW. Reflections on the pathogenesis of aortic aneurysms. Cardiovasc Surg. 2002;10:389
  19. Lopez-Candales A, Holmes DR, Liao S, et al. Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms. Am J Pathol. 1997;150:993
  20. Walton LJ, Franklin IJ, Bayston T, et al. Inhibition of prostaglandin E2 synthesis in abdominal aortic aneurysms: Implications for smooth muscle cell viability, inflammatory processes, and the expansion of abdominal aortic aneurysms. Circulation. 1999;100:48
  21. Henderson EL, Geng Y-J, Sukhova GK, et al. Death of smooth muscle cells and expression of mediators of apoptosis by T lymphocytes in human abdominal aortic aneurysms. Circulation. 1999;99:96
  22. Sinha I, Sinha-Hikim AP, Hannawa KK, et al. Mitochondrial dependent apoptosis in experimental rodent abdominal aortic aneurysms. Surgery. 2005;138:806
  23. Cai H, Harrison DG. Endothelial dysfunction in cardiovascular disease: The role of oxidant stress. Circ Res. 2000;87:840
  24. Greindling KK, Fitzgerald GA. Oxidative stress and cardiovascular injury (Part I: Basic mechanisms and in vivo monitoring of ROS). Circulation. 2003;108:1912
  25. Anidjar S, Salzmann JL, Gentric D, Langneau P, Camilleri JP, Michel JB. Elastase induced experimental aneurysms in rats. Circulation. 1990;82:973
  26. Allen RG, Tresini M. Oxidative stress and gene regulation. Free Radic Biol Med. 2000;28:463
  27. Belkhiri A, Richards C, Whaley M, McQueen SA, Orr FW. Increased expression of matrix metalloproteinase-2 by human endothelial cells after sublethal H2O2 exposure. Lab Invest. 1997;77:533
  28. Zhang HJ, Zhao W, Venkataraman S, et al. Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species. J Biol Chem. 2002;277:20919
  29. Meli DN, Christen S, Leib SL. Matrix metalloproteinase-9 in pneumococcal meningitis: Activation via an oxidative pathway. J Infect Dis. 2003;187:1411
  30. Wong GH, Goeddel DV. Induction of manganese superoxide dismutase by tumor necrosis factor: Possible protective effects. Science. 1988;242:941
  31. Masuda A, Longo DL, Kobayashi Y, Appella E, Oppenheim JJ, Matsushima K. Induction of mitochoncrial manganese superoxide dismutase by interleukin 1. FASEB J. 1988;2:3087
  32. Tsan MF, White JE, Del Vecchio PJ, Shaffer JB. IL-6 enhances TNF alpha and IL-1 induced increase of MN superoxide dismutase mRNA and O2 tolerance. Am J Physiol. 1992;263:22
  33. Yosida M, Korfhagen TR, Whitsett JA. Surfactant protein D regulates NF-kappa B and matrix metalloproteinase production in alveolar macrophages via oxidant-sensitive pathways. J Immunol. 2001;166:7514
  34. Westermark J, Kahari VM. Regulation of matrix-metalloproteinase expression in tumor invasion. FASEB J. 1999;13:781
  35. Han Z, Boyle DL, Chang L, et al. c-JUN N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest. 2001;108:73
  36. Thompson RW, Liao S, Curci JA. Vascular smooth muscle cell apoptosis in abdominal aortic aneurysms. Coron Artery Dis. 1997;8:623
  37. Tan S, Sagara Y, Liu Y, Maher P, Schubert D. The regulation of reactive oxygen species production during programmed cell death. J Cell Bio. 1998;141:1423
  38. Johnson TM, Yu ZX, Ferrans VJ, Lowenstein RA, Finkel T. Reactive oxygen species induce apoptosis of vascular smooth muscle cells. Proc Natl Acad Sci. 1996;93:11848

PII: S0022-4804(06)00385-4

doi: 10.1016/j.jss.2006.07.011

Journal of Surgical Research
Volume 138, Issue 2 , Pages 156-162 , April 2007

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