Journal of Surgical Research
Volume 141, Issue 1 , Pages 1-6 , July 2007

A Model of Heterotopic Aortic Valve Replacement for Studying Thromboembolism Prophylaxis in Mechanical Valve Prostheses

  • Stephen H. McKellar, M.D.

      Affiliations

    • Clinician Investigator Program, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine, Rochester, Minnesota
    • ,
  • Jess L. Thompson, M.D.

      Affiliations

    • Clinician Investigator Program, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine, Rochester, Minnesota
    • ,
  • Hartzell V. Schaff, M.D.

      Affiliations

    • Division of Cardiovascular Surgery, Mayo Clinic Rochester, Minnesota
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Division of Cardiovascular Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905.

Received 29 September 2006

References 

  1. Shapira Y, Sagie A, Battler A. Low-molecular-weight heparin for the treatment of patients with mechanical heart valves. Clin Cardiol. 2002;25:323
  2. Francis CW, Berkowitz SD, Comp PC, et al. Comparison of ximelagatran with warfarin for the prevention of venous thromboembolism after total knee replacement. N Engl J Med. 2003;349:1703
  3. Schulman S, Wahlander K, Lundstrom T, et al. Secondary prevention of venous thromboembolism with the oral direct thrombin inhibitor ximelagatran. N Engl J Med. 2003;349:1713
  4. Olsson SB. Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): Randomized controlled trial. Lancet. 2003;362:1691
  5. Wallentin L, Wilcox RG, Weaver WD, et al. Oral ximelagatran for secondary prophylaxis after myocardial infarction: The ESTEEM randomized controlled trial. Lancet. 2003;362:789
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  10. Gallegos RP, Nockel PJ, Rivard AL, et al. The current state of in vivo preclinical animal models for heart valve evaluation. J Heart Valve Dis. 2005;14:423
  11. Grehan JF, Hilbert SL, Ferrans VJ, et al. Development and evaluation of a swine model to assess the preclinical safety of mechanical heart valves. J Heart Valve Dis. 2000;9:710
  12. Salerno CT, Droel J, Bianco RW. Current state of in vivo preclinical heart valve evaluation. J Heart Valve Dis. 1998;7:158
  13. Bodnar E. The Medtronic Parallel valve and the lessons learned. J Heart Valve Dis. 1996;5:572
  14. Gross DR. Thromboembolic phenomena and the use of the pig as an appropriate animal model for research on cardiovascular devices. Int J Artif Organs. 1997;20:195
  15. Scott NA, Robinson KA, Nunes GL, et al. Comparison of the thrombogenicity of stainless steel and tantalum coronary stents. Am Heart J. 1995;129:866
  16. Hazekamp MG, Goffin YA, Huysmans HA. The value of the stentless biovalve prosthesis (An experimental study). Eur J Cardiothorac Surg. 1993;7:514
  17. Bonow RO, Carabello BA, Kanu C, et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease (A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease). Developed in collaboration with the Society of Cardiovascular Anesthesiologists. Endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons). Circulation. 2006;114:e84
  18. Ellis JT, Yoganathan AP. A comparison of the hinge and near-hinge flow fields of the St. Jude medical hemodynamic plus and regent bileaflet mechanical heart valves. J Thorac Cardiovasc Surg. 2000;119:83
  19. Hufnagel CA, Gomes MN. Late follow-up of ball-valve prostheses in the descending thoracic aorta. J Thorac Cardiovasc Surg. 1976;72:900
  20. Smerup M, Pedersen TF, Nyboe C, et al. A long-term porcine model for evaluation of prosthetic heart valves. Heart Surg Forum. 2004;7:E259

PII: S0022-4804(06)00616-0

doi: 10.1016/j.jss.2006.11.024

Journal of Surgical Research
Volume 141, Issue 1 , Pages 1-6 , July 2007

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