Journal of Surgical Research
Volume 142, Issue 2 , Pages 250-255 , October 2007

Ethanol Effects Proinflammatory State of Neutrophils in Shock

  • Parth B. Amin, M.D.

      Affiliations

    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Surgery, Wayne State University/University Health Center 6-C, 4201 St. Antoine, Detroit, MI 48201.
    • ,
  • Lawrence N. Diebel, M.D.
    • ,
  • David M. Liberati, M.S.

Received 6 January 2007

References 

  1. Rivara FP, Jurkovich GJ, Gurney JG, et al. The magnitude of acute and chronic alcohol abuse in trauma patients. Arch Surg. 1993;128:907
  2. Gentilello LM, Cobean RA, Walker AP, et al. Acute ethanol intoxication increases the risk of infection following penetrating abdominal trauma. J Trauma. 1993;34:669
  3. Szabo G. Consequences of alcohol consumption on host defence. Alcohol Alcohol. 1999;34:830
  4. Pallister I, Dent C, Topley N. Increased neutrophil migratory activity after major trauma: A factor in the etiology of acute respiratory distress syndrome?. Crit Care Med. 2002;30:1717
  5. Zarzaur BL, Kudsk KA. The mucosa-associated lymphoid tissue structure, function, and derangements. Shock. 2001;15:411
  6. Diebel LN, Liberati DM, Taub JS, et al. Intestinal epithelial cells modulate PMN activation and apoptosis following bacterial and hypoxic challenges. J Trauma. 2005;58:1126
  7. Artursson P, Borchardt RT. Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond. Pharm Res. 1997;14:1655
  8. Xu D, Lu Q, Kubicka R, et al. The effect of hypoxia/reoxygenation on the cellular function of intestinal epithelial cells. J Trauma. 1999;46:280
  9. Deneke C, McGowan K, Thorne G, et al. Attachment of enterotoxigenic Escherichia coli to human intestinal cells. Infect Immun. 1983;39:1102
  10. Rivara FP, Koepsell TD, Jurkovich GJ, et al. The effects of alcohol abuse on readmission for trauma. JAMA. 1993;270:1962
  11. Moore EE. Alcohol and trauma: The perfect storm. J Trauma. 2005;59:S53
  12. McDonough KH, Giaimo ME, Miller HI. Low dose ethanol alters the cardiovascular, metabolic, and respiratory compensation for severe blood loss. J Trauma. 2002;53:541
  13. Muckart DJ, Bhagwanjee S. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definitions of the systemic inflammatory response syndrome and allied disorders in relation to critically injured patients. Crit Care Med. 1997;25:1789
  14. Choudhry MA, Chaudry IH. Alcohol intoxication and post-burn complications. Front Biosci. 2006;11:998
  15. Gamble L, Mason CM, Nelson S. The effects of alcohol on immunity and bacterial infection in the lung. Med Mal Infect. 2006;36:72
  16. Esper A, Burnham EL, Moss M, et al. The effect of alcohol abuse on ARDS and multiple organ dysfunction. Minerva Anestesiol. 2006;72:375
  17. Waldschmidt TJ, Cook RT, Kovacs EJ. Alcohol and inflammation and immune responses: Summary of the 2005 Alcohol and Immunology Research Interest Group (AIRIG) meeting. Alcohol. 2006;38:121
  18. Quinton LJ, Nelson S, Zhang P, et al. Effect of systemic and local CXC chemokine administration on the EtOH-induced suppression of pulmonary neutrophil recruitment. Alcohol Clin Exp Res. 2005;7:1198
  19. Diebel LN, Liberati DM, Dulchavsky SA, et al. Ethanol impairs intestinal barrier defense by modulation of immunoglobulin A transport. Surgery. 2002;132:573
  20. Hoesel LM, Neff TA, Neff SB, et al. Harmful and protective roles of neutrophils in sepsis. Shock. 2005;24:40
  21. Brown KA, Brain SD, Pearson JD, et al. Neutrophils in development of multiple organ failure in sepsis. Lancet. 2006;368:157

PII: S0022-4804(07)00175-8

doi: 10.1016/j.jss.2007.03.025

Journal of Surgical Research
Volume 142, Issue 2 , Pages 250-255 , October 2007

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