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Journal of Surgical Research
Volume 145, Issue 2
, Pages 214-222
, April 2008
Silymarin, the Antioxidant Component of Silybum marianum, Prevents Sepsis-Induced Acute Lung and Brain Injury
References
- Neviere RR, Ceepinskas G, Madorin WS, et al. LPS pretreatment ameliorates peritonitis-induced myocardial inflammation and dysfunction: role of myocytes. Am J Physiol 999;277:H885.
- . Diversity of endotoxin-induced nitrothyrosine formation in macrophage-endothelium-rich organs. Free Rad Biol Med. 2001;31:421
- Acetylcysteine reduces respiratory burst but augments neutrophil phagocytosis in intensive care unit patients. Crit Care Med. 2001;29:272
- Milk Thistle (Silybum marianum) in PDR for Herbal Medicines. In: Montvale, NJ: Medical Economics Company; 2000;p. 516–520
- . Milk thistle. Am Family Physician. 2005;72:1285
- Stimulatory effects of silibinin and silicristin from the milk thistle Silybum marianum on kidney cells. J Pharmacol Exp Ther. 1999;290:1375
- Oxidised derivatives of silybin and their antiradical and antioxidant activity. Bioorg Med Chem. 2004;12:5677
- Inhibitory effect of a flavonoid antioxidant silymarin on benzoyl peroxide-induced tumor promotion, oxidative stress and inflammatory responses in SENCAR mouse skin. Carcinogenesis. 2000;21:811
- . Silymarin and skin cancer prevention: anti-inflammatory, antioxidant and immunomodulatory effects. (review) Int J Oncol. 2005;26:169
- . The use of N-acetylcysteine in intensive care. Crit Care Resusc. 2002;4:21
- Protective effect of beta-glucan against oxidative organ injury in a rat model of sepsis. Int Immunopharmacol. 2005;5:1387
- . Microsomal lipid peroxidation. Methods Enzymol. 1978;52:302
- . Glutathione in red blood cell metabolism (A Manual of Biochemical Methods). In: New York: Grune & Stratton; 1975;p. 112–114
- Assessment of myeloperoxidase activity in whole rat kidney. J Pharmacol Methods. 1990;24:285
- Different kinds of reactive oxygen and nitrogen species were detected in colon and breast tumors. Cancer Lett. 2001;165:219
- . Reference method for the one-stage prothrombin time test on human blood (International committee for standardization in hematology). Thromb Haemos. 1976;36:237
- Protective effects of silymarin against photocarcinogenesis in a mouse skin model. J Natl Cancer Inst. 1997;89:556
- Silymarin protects Pancreatic β-cells against cytokine-mediated toxicity: implication of c-Jun NH2-terminal kinase and janus kinase/signal transducer and activator of transcription pathways. Endocrinology. 2005;146:175
- Modulation of human polymorphonuclear leukocyte function by the flavonoid silybin. Int J Tissue React. 1988;10:223
- Amelioration of sepsis-induced hepatic and ileal injury in rats by the leukotriene receptor blocker montelukast. Prostaglandins Leukot Essent Fatty Acids. 2005;73:453
- . The role of membrane composition in ATPase activities of cirrhotic rat liver: effect of silymarin. J Appl Toxicol. 1990;10:281
- . Prevention by silymarin of membrane alterations in acute CCl4 liver damage. J Appl Toxicol. 1990;10:275
- Glutathione metabolism and its implications for health. J Nutr. 2004;134:489
- . Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes. Pharmacol Res. 1992;25:147
- Silymarin increases antioxidant enzymes in alloxan-induced diabetes in rat pancreas. Comp Biochem Physiol C Toxicol Pharmacol. 2003;136:205
- Silymarin suppresses TNF-induced activation of NF-KB, c-Jun N-terminal kinase, and apoptosis. J Immunol. 1999;163:6800
- . Myeloperoxidase. Curr Opin Hematol. 2000;7:53
- . Properties and medical use of flavonolignans (silymarin) from Silybum marianum. Phytother Res. 1996;10(suppl):S25
- Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1beta and prostaglandin E2 synthesis by silymarin. Biochem Pharmacol. 2004;67:175
- High-mobility group box 1 protein promotes development of microvascular thrombosis in rats. J Thromb Haemost. 2007;5:109
- Bench to bedside: targeting coagulation and fibrinolysis in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2006;291:L307
- . History of thromboplastin. Br J Haematol. 2000;110:248
- . Functional deficiency of erythrocyte tissue factor. Bull Exp Biol Med. 1977;83:664
- . Tissue factor: biological function and clinical significance. Saudi Med J. 2002;23:135
- Injury induced increased monocyte expression of tissue factors: factor associated with head injury attenuate the injury related monocyte expression of tissue factor. J Trauma. 2002;52:1071
- Tissue factor dependent coagulation is preferentially up-regulated within arterial branching areas in a baboon model of Escherichia coli sepsis. Am J Pathol. 2005;167:1161
- . Severe sepsis and septic shock (Definitions, epidemiology, and clinical manifestations). Crit Care Clin. 2000;16:179
PII: S0022-4804(07)00237-5
doi: 10.1016/j.jss.2007.03.072
© 2008 Elsevier Inc. All rights reserved.
« Previous
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Journal of Surgical Research
Volume 145, Issue 2
, Pages 214-222
, April 2008
