Journal of Surgical Research
Volume 147, Issue 1 , Pages 61-67 , 1 June 2008

Repair of the Thoracic Wall With an Extracellular Matrix Scaffold in a Canine Model

  • Thomas W. Gilbert, Ph.D.

      Affiliations

    • McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania
  • ,
  • Alex Nieponice, M.D.

      Affiliations

    • McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania
  • ,
  • Alan R. Spievack, M.D.

      Affiliations

    • ACell, Inc., Jessop, Maryland
  • ,
  • John Holcomb, Col., M.D., F.A.C.S.

      Affiliations

    • US Army Institute of Surgical Research, Fort Sam Houston, Texas
  • ,
  • Sebastien Gilbert, M.D.

      Affiliations

    • Department of Thoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
  • ,
  • Stephen F. Badylak, D.V.M., M.D., Ph.D.

      Affiliations

    • McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at McGowan Institute for Regenerative Medicine, University of Pittsburgh, 100 Technology Drive, Suite 200, Pittsburgh, PA 15219.

Received 23 March 2007

References 

  1. Athanassiadi K, Kalavrouziotis G, Rondogianni D, et al. Primary chest wall tumors: Early and long-term results of surgical treatment. Eur J Cardiothorac Surg. 2001;19:589
  2. Incarbone M, Pastorino U. Surgical treatment of chest wall tumors. World J Surg. 2001;25:218
  3. Vertrees A, Kellicut D, Ottman S, et al. Early definitive abdominal closure using serial closure technique on injured soldiers returning from Afghanistan and Iraq. J Am Coll Surg. 2006;202:762
  4. Losken A, Thourani VH, Carlson GW, et al. A reconstructive algorithm for plastic surgery following extensive chest wall resection. Br J Plast Surg. 2004;57:295
  5. Weyant MJ, Bains MS, Venkatraman E, et al. Results of chest wall resection and reconstruction with and without rigid prosthesis. Ann Thorac Surg. 2006;81:279
  6. Smith MD, Campbell RM. Use of a biodegradable patch for reconstruction of large thoracic cage defects in growing children. J Pediatr Surg. 2006;41:46;Discussion 46.
  7. Butler CE, Langstein HN, Kronowitz SJ. Pelvic, abdominal, and chest wall reconstruction with AlloDerm in patients at increased risk for mesh-related complications. Plast Reconstr Surg. 2005;116:1263;discussion 1276.
  8. Butler CE, Prieto VG. Reduction of adhesions with composite AlloDerm/polypropylene mesh implants for abdominal wall reconstruction. Plast Reconstr Surg. 2004;114:464
  9. Brennan EP, Reing J, Chew D, et al. Antibacterial activity within degradation products of biological scaffolds composed of extracellular matrix. Tissue Eng. 2006;12:2949
  10. Badylak SF, Kochupura PV, Cohen IS, et al. The use of extracellular matrix as an inductive scaffold for the partial replacement of functional myocardium. Cell Transplant. 2006;15(Suppl 1):S29
  11. Badylak SF, Vorp DA, Spievack AR, et al. Esophageal reconstruction with ECM and muscle tissue in a dog model. J Surg Res. 2005;128:87
  12. Nieponice A, Gilbert TW, Badylak SF. Reinforcement of esophageal anastomoses with an extracellular matrix scaffold in a canine model. Ann Thorac Surg. 2006;82:2050
  13. Robinson KA, Li J, Mathison M, et al. Extracellular matrix scaffold for cardiac repair. Circulation. 2005;112:I135
  14. Wood JD, Simmons-Byrd A, Spievack AR, et al. Use of a particulate extracellular matrix bioscaffold for treatment of acquired urinary incontinence in dogs. J Am Vet Med Assoc. 2005;226:1095
  15. Brown B, Lindberg K, Reing J, et al. The basement membrane component of biologic scaffolds derived from extracellular matrix. Tissue Eng. 2006;12:519
  16. Freytes DO, Badylak SF, Webster TJ, et al. Biaxial strength of multilaminated extracellular matrix scaffolds. Biomaterials. 2004;25:2353
  17. Gilbert TW, Stewart-Akers AM, Simmons-Byrd A, et al. Degradation and remodeling of small intestinal submucosa in canine Achilles tendon repair. J Bone Joint Surg Am. 2007;89:621
  18. Badylak SF, Coffey AC, Lantz GC, et al. Comparison of the resistance to infection of intestinal submucosa arterial autografts versus polytetrafluoroethylene arterial prostheses in a dog model. J Vasc Surg. 1994;19:465
  19. Badylak SF, Wu CC, Bible M, et al. Host protection against deliberate bacterial contamination of an extracellular matrix bioscaffold versus Dacron mesh in a dog model of orthopedic soft tissue repair. J Biomed Mater Res B Appl Biomater. 2003;67:648
  20. Jernigan TW, Croce MA, Cagiannos C, et al. Small intestinal submucosa for vascular reconstruction in the presence of gastrointestinal contamination. Ann Surg. 2004;239:733;discussion 738.
  21. Shell DH, Croce MA, Cagiannos C, et al. Comparison of small-intestinal submucosa and expanded polytetrafluoroethylene as a vascular conduit in the presence of gram-positive contamination. Ann Surg. 2005;241:995;Discussion 1001.
  22. Ueno T, Pickett LC, de la Fuente SG, et al. Clinical application of porcine small intestinal submucosa in the management of infected or potentially contaminated abdominal defects. J Gastrointest Surg. 2004;8:109
  23. Sarikaya A, Record R, Wu CC, et al. Antimicrobial activity associated with extracellular matrices. Tissue Eng. 2002;8:63

PII: S0022-4804(07)00327-7

doi: 10.1016/j.jss.2007.04.035

Journal of Surgical Research
Volume 147, Issue 1 , Pages 61-67 , 1 June 2008