Journal of Surgical Research
Volume 147, Issue 1 , Pages 1-8 , 1 June 2008

Up-Regulation of Interleukin-10 mRNA Expression in Peripheral Leukocytes Predicts Poor Outcome and Diminished Human Leukocyte Antigen-DR Expression on Monocytes in Septic Patients

  • Ryuzo Abe, M.D., Ph.D.

      Affiliations

    • Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, Chiba University, Chiba, Japan
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Ihohana, Chuo, Chiba 260-8670, Japan.
    • ,
  • Hiroyuki Hirasawa, M.D., Ph.D.

      Affiliations

    • Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, Chiba University, Chiba, Japan
    • ,
  • Shigeto Oda, M.D., Ph.D.

      Affiliations

    • Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, Chiba University, Chiba, Japan
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Ihohana, Chuo, Chiba 260-8670, Japan.
    • ,
  • Tomohito Sadahiro, M.D., Ph.D.

      Affiliations

    • Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, Chiba University, Chiba, Japan
    • ,
  • Masataka Nakamura, M.D.

      Affiliations

    • Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, Chiba University, Chiba, Japan
    • ,
  • Eizo Watanabe, M.D., Ph.D.

      Affiliations

    • Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, Chiba University, Chiba, Japan
    • ,
  • Taka-Aki Nakada, M.D., Ph.D.

      Affiliations

    • Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, Chiba University, Chiba, Japan
    • ,
  • Masahiko Hatano, M.D., Ph.D.

      Affiliations

    • Department of Developmental Genetics, Graduate School of Medicine, Chiba University, Chiba, Japan
    • ,
  • Takeshi Tokuhisa, M.D., Ph.D.

      Affiliations

    • Department of Developmental Genetics, Graduate School of Medicine, Chiba University, Chiba, Japan

Received 13 March 2007

References 

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  28. Tschaikowsky K, Hedwig-Geissing M, Schiele A, et al. Coincidence of pro- and anti-inflammatory responses in the early phase of severe sepsis: Longitudinal study of mononuclear histocompatibility leukocyte antigen-DR expression, procalcitonin, C-reactive protein, and changes in T-cell subsets in septic and postoperative patients. Crit Care Med. 2002;30:1015
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  32. Muller Kobold AC, Tulleken JE, Zijlstra JG, et al. Leukocyte activation in sepsis; correlations with disease state and mortality. Intensive Care Med. 2000;26:883
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PII: S0022-4804(07)00471-4

doi: 10.1016/j.jss.2007.07.009

Journal of Surgical Research
Volume 147, Issue 1 , Pages 1-8 , 1 June 2008

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