Journal of Surgical Research
Volume 146, Issue 1 , Pages 11-15 , 1 May 2008

Prognostic Significance of Lymph Node Metastases and Ratio in Esophageal Cancer

Presented at the 2nd Annual Academic Surgical Congress (Association for Academic Surgery), Phoenix, AZ, February 6–9, 2007.

  • Matthew Wilson, B.A.

      Affiliations

    • Department of Surgery, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
    • ,
  • Ernest L. Rosato, M.D.

      Affiliations

    • Department of Surgery, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
    • ,
  • Karen A. Chojnacki, M.D.

      Affiliations

    • Department of Surgery, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
    • ,
  • Inna Chervoneva, Ph.D.

      Affiliations

    • Division of Biostatistics, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
    • ,
  • John C. Kairys, M.D.

      Affiliations

    • Department of Surgery, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
    • ,
  • Herbert E. Cohn, M.D.

      Affiliations

    • Department of Surgery, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
    • ,
  • Francis E. Rosato Sr., M.D.

      Affiliations

    • Department of Surgery, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
    • ,
  • Adam C. Berger, M.D.

      Affiliations

    • Department of Surgery, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Surgery, Kimmel Cancer Center, Thomas Jefferson University, 1100 Walnut Street, MOB, Suite 500, Philadelphia, PA 19107

Received 8 January 2007

References 

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  2. Berger AC, Farma J, Scott WJ, et al. Complete response to neoadjuvant chemoradiotherapy in esophageal carcinoma is associated with significantly improved survival. J Clin Oncol. 2005;23:4330
  3. Walsh TN, Noonan N, Hollywood D, et al. A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. (See comment; erratum appears in N Engl J Med 1999;341:384) N Engl J Med. 1996;335:462
  4. Hofstetter W, Swisher SG, Correa AM, et al. Treatment outcomes of resected esophageal cancer. Ann Surg. 2002;236:376
  5. Korst RJ, Rusch VW, Venkatraman E, et al. Proposed review of the staging classification for esophageal cancer. J Thorac Cardiovasc Surg. 1998;115:660
  6. Nigro JJ, DeMeester SR, Hagen JA, et al. Node status in transmural esophageal adenocarcinoma and outcome after en bloc esophagectomy. J Thorac Cardiovasc Surg. 1999;117:960
  7. Bollschweiler E, Baldus SE, Schroeder W, et al. Staging of esophageal carcinoma: Length of tumor and number of involved regional lymph nodes (are these independent prognostic factors?). J Surg Oncol. 2006;94:355
  8. Eloubeidi MA, Desmond R, Arguedas MR, et al. Prognostic factors for the survival of patients with esophageal carcinoma in the United States; the importance of tumor length and lymph node status. Cancer. 2002;95:1434
  9. Anne P, Axelrod R, Rosato F, et al. A phase I trial of preoperative paclitaxel, carboplatin, 5-FU, and radiation in patients with resectable esophageal or gastric cancer. J Clin Oncol. 2004;22:4031
  10. Grambsch P, Therneau T. Proportional hazards tests and diagnostics based on weighted residuals. Biometrika. 1994;81:515
  11. Refaely Y, Krasna MJ. Multimodality therapy for esophageal cancer. Surg Clin North Am. 2002;82:729
  12. Enzinger PC, Mayer RJ. Esophageal cancer. (See comment) N Engl J Med. 2003;349:2241
  13. Berger AC, Sigurdson ER, LeVoyer T, et al. Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol. 2005;23:8706

PII: S0022-4804(07)00489-1

doi: 10.1016/j.jss.2007.07.028

Journal of Surgical Research
Volume 146, Issue 1 , Pages 11-15 , 1 May 2008

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