Journal of Surgical Research
Volume 151, Issue 1 , Pages 48-54, January 2009

Systemic Administration of Hemoglobin Vesicle Elevates Tumor Tissue Oxygen Tension and Modifies Tumor Response to Irradiation

  • Manabu Yamamoto, M.D.

      Affiliations

    • Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Yotaro Izumi, M.D., Ph.D.

      Affiliations

    • Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Division of General Thoracic Surgery, Department of Surgery, School of Medicine Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
  • ,
  • Hirohisa Horinouchi, M.D., Ph.D.

      Affiliations

    • Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Yuji Teramura, Ph.D.

      Affiliations

    • Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
  • ,
  • Hiromi Sakai, Ph.D.

      Affiliations

    • Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
  • ,
  • Mitsutomo Kohno, M.D., Ph.D.

      Affiliations

    • Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Masazumi Watanabe, M.D., Ph.D.

      Affiliations

    • Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Masafumi Kawamura, M.D., Ph.D.

      Affiliations

    • Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Takeshi Adachi, M.D., Ph.D.

      Affiliations

    • Department of Biochemistry and Integrative Medical Biology, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Eiji Ikeda, M.D., Ph.D.

      Affiliations

    • Department of Pathology, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Shinji Takeoka, Ph.D.

      Affiliations

    • Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
    • Current affiliation: Consolidated Research Institute for Advanced Science and Engineering, Waseda University, Tokyo, Japan.
  • ,
  • Eishun Tsuchida, Ph.D.

      Affiliations

    • Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
  • ,
  • Koichi Kobayashi, M.D., Ph.D.

      Affiliations

    • Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan

Received 22 September 2007 published online 13 February 2008.

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PII: S0022-4804(07)02392-X

doi:10.1016/j.jss.2007.12.770

Journal of Surgical Research
Volume 151, Issue 1 , Pages 48-54, January 2009