Journal of Surgical Research
Volume 152, Issue 2 , Pages 178-188 , April 2009

Gene Expression During Liver Regeneration After Partial Hepatectomy in Mice Lacking Type 1 Tumor Necrosis Factor Receptor

  • Tetsuya Shimizu, M.D.

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
  • ,
  • Shinji Togo, M.D., Ph.D.

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, 3–9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan
  • ,
  • Takahumi Kumamoto, M.D.

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
  • ,
  • Hirochika Makino, M.D., Ph.D.

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
  • ,
  • Tomoyuki Morita, M.D., Ph.D.

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
  • ,
  • Kuniya Tanaka, M.D., Ph.D.

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
  • ,
  • Toru Kubota, M.D., Ph.D.

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
  • ,
  • Yasushi Ichikawa, M.D., Ph.D.

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan
  • ,
  • Youji Nagasima, M.D., Ph.D.

      Affiliations

    • Department of Molecular Pathology and Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
  • ,
  • Yasushi Okazaki, M.D., Ph.D.

      Affiliations

    • Laboratory for Genome Exploration Research Group, RIKEN Genomic Science Center (GSC), Yokohama, Japan
  • ,
  • Yoshihide Hayashizaki, M.D., Ph.D.

      Affiliations

    • Laboratory for Genome Exploration Research Group, RIKEN Genomic Science Center (GSC), Yokohama, Japan
  • ,
  • Hiroshi Shimada, M.D., Ph.D.

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan

Received 13 December 2006

References 

  1. Yamada Y, Kirillova I, Peschon JJ, et al. Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type 1 tumor necrosis factor receptor. Proc Natl Acad Sci USA. 1997;94:1441
  2. Fausto N. Liver regeneration. J Hepatol. 2000;32(Suppl 1):19
  3. Michalopoulos GK, DeFrances MC. Liver regeneration. Science. 1997;276:60
  4. Shiratori Y, Hongo S, Hikiba Y, et al. Role of macrophages in regeneration of liver. Dig Dis Sci. 1996;10:1939
  5. Fujita J'Marino MW, Wada H, et al. l. Effect of TNF gene depletion on liver regeneration after partial hepatectomy in mice. Surgery. 2000;129:48
  6. Ledda-Columbano GM, Curto M, Piga R, et al. l. In vivo hepatocyte proliferation is inducible through a TNF and IL-6-independent pathway. Oncogene. 1998;17:1039
  7. Yamada Y, Webber EM, Kirillova I, et al. Analysis of liver regeneration in mice lacking type 1 or type2 tumor necrosis factor receptor: Requirement for type 1 but not type 2 receptor. Hepatology. 1998;28:959
  8. West DA, James NH, Cosulich SC, et al. Role for tumor necrosis factor receptor 1 and interleukin-1 receptor in the suppression of mouse hepatocyte apoptosis by the peroxisome proliferator nafenopin. Hepatology. 1999;30:1417;9
  9. Yamada Y, Fausto N. Deficient liver regeneration after carbon tetrachloride injury in mice lacking type 1 but not type 2 tumor necrosis factor receptor. Am J Pathol. 1998;152:1577
  10. Cressman DE, Greenbaum LE, DeAngelis RA, et al. Liver failure and deficient hepatocyte regeneration in interleukin-6-deficient mice. Science. 1996;22:1379
  11. Sakamoto T, Liu Z, Murase N, et al. Mitosis and apoptosis in the liver of interleukin-6-deficient mice after partial hepatectomy. Hepatology. 1999;29:403
  12. Aldeguer X, Debonera F, Shaked A, et al. Interleukin-6 from intrahepatic cells of bone marrow origin is required for normal marine liver regeneration. Hepatology. 2002;35:40
  13. Ren X, Hogaboam C, Carpenter A, et al. Stem cell factor restores hepatocyte proliferation in IL-6 knockout mice following 70% hepatectomy. J Clin Invest. 2003;9:1407
  14. Zimmers TA, McKillop IH, Pierce RH, et al. Massive liver growth in mice induced by systemic interleukin 6 administration. Hepatology. 2003;38:326
  15. Li W, Liang X, Leu JI, et al. Global changes in interleukin-6-dependent gene expression patterns in mouse livers after partial hepatectomy. Hepatology. 2001;33:1377
  16. Diehl AM. Cytokine regulation of liver injury and repair. Immunol Rev. 2000;174:160
  17. Campbell JS, Prichard L, Schaper F, et al. Expression of suppressors of cytokine signaling during liver regeneration. J Clin Invest. 2001;107:1285
  18. Miki R, Kadota K, Bono H, et al. Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays. Proc Natl Acad Sci USA. 2001;98:2199
  19. Bono H, Kasukawa T, Hayashizaki Y, et al. READ: RIKEN Expression Array Database. Nucleic Acids Res. 2002;30:211
  20. Kochiwa H, Suzuki R, Washio T, et al. Inferring alternative splicing patterns in mouse from a full-length cDNA library and microarray data. Genome Res. 2002;12:1286
  21. Morita T, Togo S, Kubota T, et al. Mechanism of postoperative liver failure after excessive hepatectomy investigated using a cDNA microarray. J Hepatobiliary Pancreat Surg. 2002;9:352
  22. Togo S, Makino H, Kobayashi T, et al. Mechanism of liver regeneration after partial hepatectomy using mouse cDNA microarray. J Hepatol. 2004;40:464
  23. Fukuhara Y, Hirasawa A, Li XK, et al. Gene expression profile in the regenerating rat liver after partial hepatectomy. J Hepatol. 2003;38:784
  24. Dong H, Toyoda N, Yoneyama H, et al. Gene expression profile analysis of the mouse liver during bacteria-induced fulminant hepatitis by a cDNA microarray system. Biochem Biophys Res Commun. 2002;298:675
  25. Arai M, Yokosuka O, Chiba T, et al. Gene expression profiling reveals the mechanism and pathophysiology of liver regeneration. J Biol Chem. 2003;278:29813
  26. Su AI, Guidotti LG, Pezacki JP, et al. Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice. Proc Natl Acad Sci USA. 2002;99:11181
  27. Loughnane NK, Sabla GE, Ebert CL, et al. Independent and overlapping transcriptional activation during liver development and regeneration in mice. Hepatology. 2002;35:525
  28. Higgins GM, Anderson RM. Experimental pathology of the liver, I (Restoration of the liver of the white rat following partial surgical removal). Arch Pathol. 1931;12:186
  29. Kooby DA, Zakian KL, Challa SN, et al. Use of phosphorus-31 nuclear magnetic response spectroscopy to determine safe timing of chemotherapy after hepatic resection. Cancer Res. 2000;60:3800
  30. Carninci P, Kvam C, Kitamura A, et al. High-efficiency full-length cDNA cloning by biotinylated CAP trapper. Genomics. 1996;37:327
  31. Kadota K, Miki R, Bono H, et al. Preprocessing implementation for microarray (PRIM): An efficient method for processing cDNA microarray data. Physiol Gen. 2001;19:183
  32. Akkerman P, Cote P, Yang SQ, et al. Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy. Am J Physiol. 1992;263:G579
  33. Koay MA, Christman JW, Wudel LJ, et al. Modulation of endotoxin-induced NF-kappa-B activation in lung and liver through TNF type 1 and IL-1 receptors. Am J Physiol Lung Cell Mol Physiol. 2002;283:L1247
  34. Yang Q, Kim YS, Lin Y, Lewis , et al. Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK. EMBO Rep. 2006;7:622
  35. Dixit A, Rae AR. Influence of 2-mercaptopropionylglycine on DMBA-induced biochemical changes in regenerating mouse liver: 1. Key enzymes of glycolysis and lactate dehydrogenase. Biochem Int. 1983;7:695

PII: S0022-4804(07)02431-6

doi: 10.1016/j.jss.2007.12.785

Journal of Surgical Research
Volume 152, Issue 2 , Pages 178-188 , April 2009