Journal of Surgical Research
Volume 153, Issue 1 , Pages 66-70 , 1 May 2009

Role of Cardiopulmonary Bypass and Arrested Heart Status in the Early Cell Distribution after Intracoronary Infusion of Bone Marrow Stromal Cells

  • Peng Song, M.D.

      Affiliations

    • Research Center for Cardiac Regenerative Medicine, the Ministry of Health and Department of Surgery, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, China
    • ,
  • Hao Zhang, M.D., Ph.D.

      Affiliations

    • Research Center for Cardiac Regenerative Medicine, the Ministry of Health and Department of Surgery, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, China
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Surgery, Research Center for Cardiac Regenerative Medicine, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167A Beilishilu, Beijing 100037, P.R. China
    • ,
  • Ming-jie Lu, M.D.

      Affiliations

    • Unit of Magnetic Resonance Imaging, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    • ,
  • Jun Li, B.Sc.

      Affiliations

    • Research Center for Cardiac Regenerative Medicine, the Ministry of Health and Department of Surgery, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, China
    • ,
  • Xue-wen Liu, M.Sc.

      Affiliations

    • Research Center for Cardiac Regenerative Medicine, the Ministry of Health and Department of Surgery, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, China
    • ,
  • Ying-jie Wei, Ph.D.

      Affiliations

    • Research Center for Cardiac Regenerative Medicine, the Ministry of Health and Department of Surgery, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, China
    • ,
  • Sheng-shou Hu, M.D.

      Affiliations

    • Research Center for Cardiac Regenerative Medicine, the Ministry of Health and Department of Surgery, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, China

Received 26 December 2007

References 

  1. Wu KH, Liu YL, Zhou B, et al. Cellular therapy and myocardial tissue engineering: The role of adult stem and progenitor cells. Eur J Cardiothorac Surg. 2006;30:770
  2. Freyman T, Polin G, Osman H, et al. A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. Eur Heart J. 2006;27:1114
  3. Zhang H, Song P, Tang Y, et al. Injection of bone marrow mesenchymal stem cells in the borderline area of infarcted myocardium: Heart status and cell distribution. J Thorac Cardiovasc Surg. 2007;134:1234
  4. Hou M, Yang KM, Zhang H, et al. Transplantation of mesenchymal stem cells from human bone marrow improves damaged heart function in rats. Int J Cardiol. 2007;115:220
  5. He G, Zhang H, Wei H, et al. In vivo imaging of bone marrow mesenchymal stem cells transplanted into myocardium using magnetic resonance imaging: A novel method to trace the transplanted cells. Int J Cardiol. 2007;114:4
  6. Amado LC, Schuleri KH, Saliaris AP, et al. Multimodality noninvasive imaging demonstrates in vivo cardiac regeneration after mesenchymal stem cell therapy. J Am Coll Cardiol. 2006;48:2116
  7. Anderson LJ, Holden S, Davis B, et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J. 2001;22:2171
  8. Bos C, Delmas Y, Desmouliere A, et al. In vivo MR imaging of intravascularly injected magnetically labeled mesenchymal stem cells in rat kidney and liver. Radiology. 2004;233:781
  9. Hou D, Youssef EA, Brinton TJ, et al. Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: Implications for current clinical trials. Circulation. 2005;112:1150
  10. Dai W, Hale SL, Martin BJ, et al. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: Short- and long-term effects. Circulation. 2005;112:214

PII: S0022-4804(08)00193-5

doi: 10.1016/j.jss.2008.03.009

Journal of Surgical Research
Volume 153, Issue 1 , Pages 66-70 , 1 May 2009

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