Journal of Surgical Research
Volume 157, Issue 1 , Pages 48-54 , November 2009

Hepatosplanchnic Ischemia/Reperfusion is a Major Determinant of Lung Vascular Injury After Aortic Surgery

  • Alexander D. Cornet, M.D. M.Sc.

      Affiliations

    • Department of Intensive Care, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands
    • ,
  • Sandra D.K. Kingma, M.Sc.

      Affiliations

    • Department of Intensive Care, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands
    • ,
  • Ronald J. Trof, M.D., M.Sc.

      Affiliations

    • Department of Intensive Care, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands
    • ,
  • Willem Wisselink, M.D. Ph.D.

      Affiliations

    • Department of Vascular Surgery, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands
    • Institute for Cardiovascular Research, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands
    • ,
  • A.B. Johan Groeneveld, M.D., Ph.D.

      Affiliations

    • Department of Intensive Care, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands
    • Institute for Cardiovascular Research, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Intensive Care, Vrije Universiteit University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

Received 13 April 2008

References 

  1. Diehl JT, Cali RF, Hertzer NR, et al. Complications of abdominal aortic reconstruction. An analysis of perioperative risk factors in 557 patients. Ann Surg. 1983;197:49
  2. Vodinh J, Bonnet F, Touboul C, et al. Risk factors of postoperative pulmonary complications after vascular surgery. Surgery. 1989;105:360
  3. Svensson LG, Hess KR, Coselli JS, et al. A prospective study of respiratory failure after high-risk surgery on the thoracoabdominal aorta. J Vasc Surg. 1991;14:271
  4. Raijmakers PG, Groeneveld AB, Rauwerda JA, et al. Transient increase in interleukin-8 and pulmonary microvascular permeability following aortic surgery. Am J Respir Crit Care Med. 1995;151:698
  5. Groeneveld AB, Raijmakers PG, Rauwerda JA, et al. The inflammatory response to vascular surgery-associated ischemia and reperfusion in man: Effect on postoperative pulmonary function. Eur J Vasc Endovasc Surg. 1997;14:351–359
  6. Raijmakers PGHM, Groeneveld ABJ, Rauwerda JA, et al. Acute lung injury after aortic surgery: The relation between lung and leg microvascular permeability to 111Indium-labelled transferrin and circulating mediators. Thorax. 1997;52:866–871
  7. Parajasingam R, Nicholson ML, Bell PRF, et al. Noncardiogenic pulmonary edema in vascular surgery. Eur J Vasc Endovasc Surg. 1999;17:93
  8. Groeneveld ABJ, Verheij J, Berg Van den, et al. Increased pulmonary capillary permeability and extravascular lung water after major vascular surgery: Effect on radiography and ventilatory variables. Eur J Anaesthesiol. 2006;23:36
  9. Money SR, Rice K, Crockett D, et al. Risk of respiratory failure after repair of thoracoabdominal aortic aneurysms. Am J Surg. 1994;168:152
  10. Bux J, Sachs JH. The pathogenesis of transfusion-related acute lung injury (TRALI). Br J Haematol. 2007;136:788
  11. Soong CV, Blair PHB, Halliday MI, et al. Endotoxaemia, the generation of the cytokines and their relationship to intramucosal acidosis of the sigmoid colon in elective abdominal aortic aneurysm repair. Eur J Vasc Surg. 1993;7:534
  12. Koike K, Moore EE, Moore FA, et al. Gut ischemia/reperfusion produces lung injury independent of endotoxin. Crit Care Med. 1994;22:1438
  13. Iglesias JL, LaNoue JL, Rogers TE, et al. Physiologic basis of pulmonary edema during intestinal reperfusion. J Surg Res. 1998;80:156
  14. Holzheimer RG, Gross J, Schein M. Pro- and anti-inflammatory cytokine-response in abdominal aortic aneurysm repair: A clinical model of ischemia-reperfusion. Shock. 1999;11:305
  15. Souza AL, Poggetti RS, Fontes B, et al. Gut ischemia/reperfusion activates lung macrophages for tumor necrosis factor and hydrogen peroxide production. J Trauma. 2000;49:232
  16. Welborn MB, Oldenburg HAS, Hess PJ, et al. The relationship between visceral ischemia, proinflammatory cytokines, and organ injury in patients undergoing thoracoabdominal aortic aneurysm repair. Crit Care Med. 2000;28:3191
  17. Edrees WK, Lau LL, Young IS, et al. The effect of lower limb ischemia-reperfusion on intestinal permeability and the systemic inflammatory response. Eur J Vasc Endovasc Surg. 2003;35:330
  18. Lammers KM, Innocenti G, Venturi A, et al. The effect of transient intestinal ischemia on inflammatory parameters. Int J Colorectal Dis. 2003;18:78
  19. Adembri C, Kastamoniti E, Bertolozzi I, et al. Pulmonary injury follows systemic inflammatory reaction in infrarenal aortic surgery. Crit Care Med. 2004;32:1170
  20. Harkin DW, Rubin BB, Romaschin A, et al. Selective inducible nitric oxide (iNOS) inhibition attenuates remote acute lung injury in a model of ruptured abdominal aortic aneurysm. J Surg Res. 2004;120:230
  21. Norwood MGA, Bown MJ, Sayers RD. Ischemia-reperfusion injury and regional inflammatory responses in abdominal aortic aneurysm repair. Eur J Vasc Endovasc Surg. 2004;28:234
  22. Norwood MGA, Bown MJ, Sutton AJ, et al. Interleukin 6 production during abdominal aortic aneurysm repair arises from the gastrointestinal tract and not the legs. Br J Surg. 2004;91:1153
  23. Norwood MGA, Horsburgh T, Bown MJ, et al. Neutrophil activation occurs in the lower limbs of patients undergoing elective repair of abdominal aortic aneurysm. Eur J Vasc Endovasc Surg. 2005;29:390
  24. Harkin DW, Arnold R, Hoper M. Anti-endotoxin hyper immune globulin attenuates portal cytokinaemia, phagocytic cell priming, and acute lung injury after lower limb ischemia-reperfusion injury. Eur J Vasc Endovasc Surg. 2007;33:330
  25. Harward TR, Welborn MB, Martin TD, et al. Visceral ischemia and organ dysfunction after thoracoabdominal aortic aneurysm repair: A clinical and cost analysis. Ann Surg. 1996;223:729
  26. Back MR, Bandyk M, Bradner M, et al. Critical analysis of outcome determinants affecting repair of intact aneurysms involving the visceral aorta. Ann Vasc Surg. 2005;19:648
  27. Collange O, Fabienne T, Nathalie R, et al. Pulmonary apoptosis after supraceliac aortic clamping in a rat model. J Surg Res. 2005;129:190
  28. Jiang H, Meng F, Li W, et al. Splenectomy ameliorates acute multiple organ damage induced by liver warm ischemia reperfusion in rats. Surgery. 2007;141:32
  29. Szwerc MF, Benckart DH, Lin JC, et al. Recent clinical experience with left heart bypass using a centrifugal pump for repair of traumatic aortic transection. Ann Surg. 1999;230:484
  30. Knaus WA, Draper EA, Wagner DP, et al. APACHE II: A severity of disease classification system. Crit Care Med. 1985;13:818
  31. Murray JF, Matthay MA, Luce JM, et al. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis. 1988;138:720
  32. Ditmarsch M, Yilmaz EN, Vahl AC, et al. Endoluminal aortic shunting for distal perfusion during thoracic aortal cross-clamping in a pig model. Cardiovasc Surg. 2003;11:287
  33. Brown DJ, Schermerhorn ML, Powell RJ, et al. Mesenteric stenting for chronic mesenteric ischemia. J Vasc Surg. 2005;42:268
  34. Atkins MD, Kwolek CJ, LaMuraglia GM, et al. Surgical revascularization versus endovascular therapy for chronic mesenteric ischemia: A comparative experience. J Vasc Surg. 2007;45:1162
  35. Harward TR, Welborn MB, Martin TD, et al. Visceral ischemia and organ dysfunction after thoracoabdominal aortic aneurysm repair: A clinical and cost analysis. Ann Surg. 1996;223:729

PII: S0022-4804(08)00612-4

doi: 10.1016/j.jss.2008.09.021

Journal of Surgical Research
Volume 157, Issue 1 , Pages 48-54 , November 2009

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