Journal of Surgical Research
Volume 158, Issue 1 , Pages 20-27 , January 2010

Risk of Adverse Outcomes Associated With Blood Transfusion After Cardiac Surgery Depends on the Amount of Transfusion1

  • Bryan A. Whitson, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Division of Cardiovascular and Thoracic Surgery, University of Minnesota, Minneapolis, Minnesota
    • ,
  • Stephen J. Huddleston, M.D.

      Affiliations

    • Department of Surgery, Division of Cardiovascular and Thoracic Surgery, University of Minnesota, Minneapolis, Minnesota
    • ,
  • Kay Savik, M.S.

      Affiliations

    • School of Nursing, University of Minnesota, Minneapolis, Minnesota
    • ,
  • Sara J. Shumway, M.D.

      Affiliations

    • Department of Surgery, Division of Cardiovascular and Thoracic Surgery, University of Minnesota, Minneapolis, Minnesota
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Division of Cardiovascular and Thoracic Surgery, University of Minnesota, 420 Delaware Street SE, MMC 207, Minneapolis, MN 55455.

Received 27 May 2008

References 

  1. Stover EP, Siegel LC, Parks R, et al. Variability in transfusion practice for coronary artery bypass surgery persists despite national consensus guidelines: A 24-institution study. Institutions of the Multicenter Study of Perioperative Ischemia Research Group. Anesthesiology. 1998;88:327
  2. Lundsgaard-Hansen P. Safe hemoglobin or hematocrit levels in surgical patients. World J Surg. 1996;20:1182
  3. Haller M, Forst H. Red cell transfusion therapy in the critical care setting. Transfus Sci. 1997;18:459
  4. Whitson BA, Huddleston SJ, Savik K, et al. Bloodless cardiac surgery is associated with decreased morbidity and mortality. J Card Surg. 2007;22:373
  5. Ferraris VA, Ferraris SP, Saha SP, et al. Perioperative blood transfusion and blood conservation in cardiac surgery: The Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline. Ann Thorac Surg. 2007;83:S27
  6. Murphy GJ, Reeves BC, Rogers CA, et al. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation. 2007;116:2544
  7. Leal-Noval SR, Rincon-Ferrari MD, Garcia-Curiel A, et al. Transfusion of blood components and postoperative infection in patients undergoing cardiac surgery. Chest. 2001;119:1461
  8. Rogers MA, Blumberg N, Heal JM, et al. Increased risk of infection and mortality in women after cardiac surgery related to allogeneic blood transfusion. J Womens Health (Larchmt). 2007;16:1412
  9. Scott BH, Seifert FC, Grimson R. Blood transfusion is associated with increased resource utilization, morbidity and mortality in cardiac surgery. Ann Card Anaesth. 2008;11:15
  10. Cosgrove DM, Loop FD, Lytle BW, et al. Determinants of blood utilization during myocardial revascularization. Ann Thorac Surg. 1985;40:380
  11. Magovern JA, Sakert T, Benckart DH, et al. A model for predicting transfusion after coronary artery bypass grafting. Ann Thorac Surg. 1996;61:27
  12. Moskowitz DM, Klein JJ, Shander A, et al. Predictors of transfusion requirements for cardiac surgical procedures at a blood conservation center. Ann Thorac Surg. 2004;77:626
  13. Zacharias A, Habib RH. Factors predisposing to median sternotomy complications. Deep vs superficial infection. Chest. 1996;110:1173
  14. Michalopoulos A, Stavridis G, Geroulanos S. Severe sepsis in cardiac surgical patients. Eur J Surg. 1998;164:217

PII: S0022-4804(08)00664-1

doi: 10.1016/j.jss.2008.10.015

Journal of Surgical Research
Volume 158, Issue 1 , Pages 20-27 , January 2010

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