Journal of Surgical Research
Volume 157, Issue 1 , Pages 2-3 , November 2009

Cell Transplantation in the Treatment of Acute Liver Injury: Effect But No Clear Mechanism

  • Tareq Massimi, M.D.

      Affiliations

    • Department of Surgery, Berkshire Medical Center, Pittsfield, Massachusetts
    • ,
  • Shimul A. Shah, M.D.

      Affiliations

    • Department of Surgery, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, Massachusetts
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Surgery, UMass Memorial Medical Center, University of Massachusetts Medical School, 55 Lake North Avenue, Worcester, MA 01655.

Received 11 January 2009

References 

  1. O'Grady J. Modern management of acute liver failure. Clin Liver Dis. 2007;11:291
  2. Nussler A, Konig S, Ott M, et al. Present status and perspectives of cell-based therapies for liver diseases. J Hepatol. 2006;45:144
  3. Zhang B, Inagaki M, Jiang B, et al. Effects of bone marrow and hepatocyte transplantation on liver injury. J Surg Res. 2009;157:71
  4. Wang X, Montini E, Al-Dhalimy M, et al. Kinetics of liver repopulation after bone marrow transplantation. Am J Pathol. 2002;161:565
  5. Seppen J, van der Rijt R, Looije N, et al. Long-term correction of bilirubin UDPglucuronyltransferase deficiency in rats by in utero lentiviral gene transfer. Mol Ther. 2003;8:593
  6. Rosen ED, Chan JC, Idusogie E, et al. Mice lacking factor VII develop normally but suffer fatal perinatal bleeding. Nature. 1997;390:290
  7. Kumaran V, Benten D, Follenzi AJ, et al. Transplantation of endothelial cells corrects the phenotype in hemophilia A mice. J Thromb Haemost. 2005;3:2022

PII: S0022-4804(09)00280-7

doi: 10.1016/j.jss.2009.05.023

Journal of Surgical Research
Volume 157, Issue 1 , Pages 2-3 , November 2009

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