Journal of Surgical Research
Volume 159, Issue 1 , Pages e11-e16 , March 2010

Pretreatment with Dexmedetomidine or Thiopental Decreases Myoclonus after Etomidate: A Randomized, Double-Blind Controlled Trial

  • Ayse Mizrak, M.D.

      Affiliations

    • Department of Anesthesiology and Reanimation, Gaziantep University School of Medicine Gaziantep, Turkey
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Anesthesiology and Reanimation, Gaziantep University Medical Faculty, 27310 Sahinbey, Gaziantep, Turkey.
    • ,
  • Senem Koruk, M.D.

      Affiliations

    • Department of Anesthesiology and Reanimation, Gaziantep University School of Medicine Gaziantep, Turkey
    • ,
  • Murat Bilgi, M.D.

      Affiliations

    • Department of Anesthesiology and Reanimation, Gaziantep University School of Medicine Gaziantep, Turkey
    • ,
  • Betul Kocamer, M.D.

      Affiliations

    • Department of Anesthesiology and Reanimation, Gaziantep University School of Medicine Gaziantep, Turkey
    • ,
  • Ibrahim Erkutlu, M.D.

      Affiliations

    • Department of Neurosurgery, Gaziantep University School of Medicine Gaziantep, Turkey
    • ,
  • Suleyman Ganidagli, M.D.

      Affiliations

    • Department of Anesthesiology and Reanimation, Gaziantep University School of Medicine Gaziantep, Turkey
    • ,
  • Unsal Oner, M.D.

      Affiliations

    • Department of Anesthesiology and Reanimation, Gaziantep University School of Medicine Gaziantep, Turkey

Received 7 April 2009

References 

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  2. Hueter L, Schwarzkopf K, Simon M, et al. Pretreatment with sufentanil reduces myoclonus after etomidate. Acta Anaesthesiol Scand. 2003;47:482
  3. Doenicke AW, Roizen MF, Kugler J, et al. Reducing myoclonus after etomidate. Anesthesiology. 1999;90:113
  4. Schwarzkopf KR, Hueter L, Simon M, et al. Midazolam pretreatment reduces etomidate-induced myoclonic movements. Anaesth Intensive Care. 2003;31:18
  5. Guler A, Satilmis T, Akinci SB, et al. Magnesium sulfate pretreatment reduces myoclonus after etomidate. Anesth Analg. 2005;101:705
  6. Kelsaka E, Karakaya D, Sarihasan B, et al. Remifentanil pretreatment reduces myoclonus after etomidate. J Clin Anesth. 2006;18:83
  7. Fassoulaki A, Pateras C, Kaniaris P. [Fentanyl in the prevention of etomidate-induced myoclonus]. Cah Anesthesiol. 1987;35:201
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  15. Liou JT, Hsu JC, Liu FC, et al. Pretreatment with small-dose ketamine reduces withdrawal movements associated with injection of rocuronium in pediatric patients. Anesth Analg. 2003;97:1294
  16. Bekker A, Sturaitis MK. Dexmedetomidine for neurological surgery. Neurosurgery. 2005;57:1;discussion 11
  17. Aho MS, Erkola OA, Scheinin H, et al. Effect of intravenously administered dexmedetomidine on pain after laparoscopic tubal ligation. Anesth Analg. 1991;73:112
  18. Memis D, Turan A, Karamanlioglu B, et al. Adding dexmedetomidine to lidocaine for intravenous regional anesthesia. Anesth Analg. 2004;98:835
  19. Liu H, Dai T, Yao S. Effect of thiopental sodium on N-methyl-D-aspartate-gated currents. Can J Anaesth. 2006;53:442
  20. Venn RM, Bradshaw CJ, Spencer R, et al. Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit. Anaesthesia. 1999;54:1136
  21. Tatsuo MA, Yokoro CM, Salgado JV, et al. Hyperalgesic effect induced by barbiturates, midazolam and ethanol: Pharmacological evidence for GABA-A receptor involvement. Revista brasileira de pesquisas medicas e biologicas/Sociedade Brasileira de Biofisica. Brazilian J Med Biol Res. 1997;30:251
  22. Archer DP, Ewen A, Roth SH, et al. Plasma, brain, and spinal cord concentrations of thiopental associated with hyperalgesia in the rat. Anesthesiology. 1994;80:168
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PII: S0022-4804(09)00400-4

doi: 10.1016/j.jss.2009.07.031

Journal of Surgical Research
Volume 159, Issue 1 , Pages e11-e16 , March 2010

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