Journal of Surgical Research
Volume 171, Issue 1 , Pages 300-310 , November 2011

RhGH Attenuates Ischemia Injury of Intrahepatic Bile Ducts Relating to Liver Transplantation

  • Zheng Wang, M.D.
    • ,
  • Jie Zhou, M.M.

      Affiliations

    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Hepatobiliary Surgery, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou 510515, China.
    • ,
  • Jianhua Lin, M.D.
    • ,
  • Yu Wang, M.D.
    • ,
  • Yixiong Lin, M.D.
    • ,
  • Xianghong Li, M.D.

Received 11 September 2009

References 

  1. Pascher A, Neuhaus P. Bile duct complications after liver transplantation. Transpl Int. 2005;18:627
  2. Cameron AM, Busuttil RW. Ischemic cholangiopathy after liver transplantation. Hepatobiliary Pancreat Dis Int. 2005;4:495
  3. Demetris AJ, Fontes P, Lunz JG, et al. Wound healing in the biliary tree of liver allografts. J Cell Transplant. 2006;15:S57
  4. Nishida S, Nakamura N, Kadono J, et al. Intrahepatic biliary strictures after liver transplantation. J Hepatobiliary Pancreas Surg. 2006;13:511
  5. Rull R, Garcia Valdecasas JC, Grande L, et al. Intrahepatic biliary lesions after orthotopic liver transplantation. Transpl Int. 2001;14:129
  6. Carroll PV, Jackson NC, Russell Jones DL, et al. Combined growth hormone/insulin-like growth factor-I in addition to glutamine supplemented TPN results in net protein anabolism in critical illness. Am J Physiol Endocrinol Metab. 2004;286:E151
  7. Krupczak-Hollis K, Wang X, Dennewitz MB, et al. Growth hormone stimulates proliferation of old-aged regenerating liver through forkhead box m1b. Hepatology. 2003;38:1552
  8. Alvaro D, Mancino MG, Glaser S, et al. Proliferating cholangiocytes: A neuroendocrine compartment in the diseased liver. Gastroenterology. 2006;132:415
  9. Zhao H, Zhou J. Establishment of an orthotopic autologous liver transplantation model with bile ducts ischemia-reperfusion injury in rats. Acad J Sec Milit Med Univ. 2006;27:429
  10. Luo Z, Zhang Y, Han B, Wang H, et al. Establishment of orthotopic liver autotransplantation in rats with portal-cervical bypass. J Dig Surg. 2005;4:219
  11. Li H, Dong J, Zhang Y. The effect of autocrine VEGF of intra-hepatic cholangiocytes after liver transplantation with ischemia of hepatic artery. Chin J Curr Adv Gen Surg. 2007;10:124
  12. Wu T, Yang G, Zhao J, et al. Rapamycin inhibits compensatory bile duct growth after ischemia injury. Acad J Sec Milit Med Univ. 2008;29:800
  13. Strazzabosco M, Fabris L, Spirli C. Pathophysiology of cholangiopathies. J Clin Gastroenterol. 2005;S90
  14. Alvaro D, Drudi-Metalli V, Gianfranco Alpini G, et al. The intrahepatic biliary epithelium is a target of the growth hormone/insulin-like growth factor 1 axis. J Hepatol. 2005;43:875
  15. Gatto M, Drudi-Metalli V, Torrice A, et al. Insulin-like growth factor-1 isoforms in rat hepatocytes and cholangiocytes and their involvement in protection against cholestatic injury. Lab Invest. 2008;88:986
  16. Bogert PT, LaRusso NF. Cholangiocyte biology. Curr Opinion Gastroenterol. 2007;23:299
  17. Brusselmans K, Bono F, Collen D, et al. A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia. J Biol Chem. 2005;80:3493
  18. Gaudio E, Barbaro B, Alvaro D, et al. Vascular endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism. Gastroenterology. 2006;130:1270

PII: S0022-4804(10)00099-5

doi: 10.1016/j.jss.2010.02.003

Journal of Surgical Research
Volume 171, Issue 1 , Pages 300-310 , November 2011

Article Tools

* Image Usage & Resolution