Journal of Surgical Research
Volume 164, Issue 1 , Pages e201-e212 , November 2010

The Importance of Engraftment in Flap Revascularization: Confirmation by Laser Speckle Perfusion Imaging

  • Paul G. McGuire, Ph.D.

      Affiliations

    • Department of Cell Biology and Physiology, University of New Mexico HSC, Albuquerque, New Mexico
    • ,
  • Thomas R. Howdieshell, M.D.

      Affiliations

    • Department of Surgery, University of New Mexico HSC, Albuquerque, New Mexico
    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Department of Surgery, MSC10-5610, University of New Mexico HSC, Albuquerque, NM 87131.

Received 20 June 2010

References 

  1. Isner JM. Tissue responses to ischemia: Local and remote responses for preserving perfusion of ischemic muscle. J Clin Invest. 2000;106:615
  2. Balasubramani M, Kumar TR, Babu M. Skin substitutes: A review. Burns. 2001;27:534
  3. Schechner JS, Crane SK, Wang F. Engraftment of humanized skin equivalents. FASEB J. 2003;17:2250
  4. Diaz-Sandoval LJ, Losordo DW. Gene therapy for cardiovascular angiogenesis. Expert Opin Biol Ther. 2003;3:599
  5. Choksy SA, Chan P. Therapeutic angiogenesis. Br J Surg. 2006;93:261
  6. Barac A, Campia U, Panze JA. Methods for evaluating endothelial function in humans. Hypertension. 2007;49:748
  7. Briers JD. Laser Doppler, speckle and related techniques for blood perfusion mapping and imaging. Physiol Meas. 2001;22:R35
  8. Choi B, Kang NM, Nelson JS. Laser speckle imaging for monitoring blood flow dynamics in the in vivo rodent dorsal skin fold model. Microvasc Res. 2004;68:143
  9. Leahy MJ, Enfield JG, Clancy NT, et al. Biphotonic methods in microcirculation imaging. Medical Laser Application. 2007;22:105
  10. Moloney TC, Dockery P, Windebank AJ, et al. Survival and immunogenicity of mesenchymal stem cells from the green fluorescent protein transgenic rodent. Neurorehab Neural Repair. 2010;12:1
  11. Heil M, Eitenmuller I, Schmitz-Rixen T, et al. Arteriogenesis versus angiogenesis: Similarities and differences. J Cell Mol Med. 2006;10:45
  12. Unger EF, Sheffield CD, Epstein SE. Heparin promotes the formation of extracardiac to coronary anastomoses in a canine model. Am J Physiol. 1991;260:H1625
  13. Scholz D, Ziegelhoeffer T, Helisch A, et al. Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice. J Mol Cell Cardiol. 2002;34:775
  14. Schaper W, Scholz D. Factors regulating arteriogenesis. Arterioscler Thromb Vasc Biol. 2003;23:1143
  15. Schaper W. Collateral circulation: Past and present. Basic Res Cardiol. 2009;104:5
  16. Garcia-Cardena G, Comander J, Anderson KR, et al. Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proc Natl Acad Sci USA. 2001;98:4478
  17. Shireman PK. The chemokine system in arteriogenesis and hindlimb ischemia. J Vasc Surg. 2007;45:48A
  18. O’Doherty J, McNamara P, Clancy NT, et al. Comparison of instruments for investigation of microcirculatory blood flow and red blood cell concentration. J Biomed Optics. 2009;14:1
  19. Oberg PA, Tenland T, Nilsson GE. Laser Doppler flowmetry-a noninvasive and continuous method for blood flow evaluation in microvascular studies. Acta Med Scand Suppl. 1984;687:17
  20. Arildsson ML, Wardell K, Nilsson GE. Higher order moment processing of laser Doppler perfusion signals. J Biomed Optics. 1997;2:358
  21. Fercher F, Briers JD. Flow visualization by means of single-exposure speckle photography. Opt Commun. 1981;37:326
  22. O’Doherty J, Henricson J, Anderson C, et al. Subepidermal imaging using polarized light spectroscopy for assessment of skin microcirculation. Skin Res Technol. 2007;13:472
  23. Nilsson GE, Zhai H, Farahmand S, et al. Cutaneous bioengineering instrumentation standardization: The tissue viability imager. Skin Res Technol. 2009;15:6
  24. Carmeliet P. Angiogenesis in health and disease. Nature Med. 2003;9:653
  25. Adams RH, Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis. Nature Rev Molec Cell Biol. 2007;8:464
  26. Van Royen N, Piek JJ, Schaper W, et al. A critical review of clinical arteriogenesis research. J Am Coll Cardiol. 2010;55:17

PII: S0022-4804(10)00675-X

doi: 10.1016/j.jss.2010.07.059

Journal of Surgical Research
Volume 164, Issue 1 , Pages e201-e212 , November 2010

Article Tools

* Image Usage & Resolution