Journal of Surgical Research
Volume 164, Issue 2 , Pages e253-e256 , December 2010

Staged-Injection Procedure to Prevent Cement Leakage During Vertebroplasty: An In Vitro Study

  • Zi-xiang Wu, M.D.
  • ,
  • Da Liu, M.D.
  • ,
  • Shi-yong Wan, M.D.
  • ,
  • Hong-xun Sang, M.D.
  • ,
  • Wei Lei, M.D.

      Affiliations

    • Corresponding Author InformationTo whom correspondence and reprint requests should be addressed at Institute of Orthopaedics, Xijing Hospital, no.17 Changlexi Road, Xi’an Shaanxi Province, P.R. China 710032.

Received 27 March 2010

References 

  1. Barr JD, Barr MS, Lemley TJ, et al. Percutaneous vertebroplasty for pain relief and spinal stabilization. Spine. 2000;25:923
  2. Deramond H, Depriester C, Galibert P, et al. Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results. Radiol Clin North Am. 1998;36:533
  3. Murphy KJ, Lin DD. Vertebroplasty: A simple solution to a difficult problem. J Clin Densitom. 2001;4:189
  4. Garfin SR, Yuan HA, Reiley MA. New technologies in spine: Kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine. 2001;26:1511
  5. Shapiro S, Abel T, Purvines S. Surgical removal of epidural and intradural polymethylmethacrylate extravasation complicating percutaneous vertebroplasty for an osteoporotic lumbar compression fracture. J Neurosurg. 2003;98:90
  6. Watts NB, Harris ST, Genant HK. Treatment of painful osteoporotic vertebral fractures with percutaneous vertebroplasty or kyphoplasty. Osteoporos Int. 2001;12:429
  7. Schmidt R, Cakir B, Mattes T, et al. Cement leakage during vertebroplasty: An underestimated problem?. Eur Spine J. 2005;14:466
  8. Grados F, Depriester C, Cayrolle G, et al. Long-term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Rheumatology (Oxford). 2000;39:1410
  9. Harrington KD. Major neurological complications following percutaneous vertebroplasty with polymethylmethacrylate: A case report. J Bone Joint Surg Am. 2001;83:1070
  10. Ratliff J, Nguyen T, Heiss J. Root and spinal cord compression from methylmethacrylate vertebroplasty. Spine. 2001;26:300
  11. Padovani B, Kasriel O, Brunner P, et al. Pulmonary embolism caused by acrylic cement: A rare complication of percutaneous vertebroplasty. Am J Neuroradiol. 1999;20:375
  12. Scroop R, Eskridge J, Britz GW. Paradoxical cerebral arterial embolization of cement during intraoperative vertebroplasty: Case report. Am J Neuroradiol. 2002;23:868
  13. Jang JS, Lee SH, Jung SK. Pulmonary embolism of polymethylmethacrylate after percutaneous vertebroplasty: A report of three cases. Spine. 2002;27:416
  14. Lee BJ, Lee SR, Yoo TY. Paraplegia as a complication of percutaneous vertebroplasty with polymethylmethacrylate: A case report. Spine. 2002;27:419
  15. Childers JC. Cardiovascular collapse and death during vertebroplasty. Radiology. 2003;228:902
  16. Mathis JM, Wong W. Percutaneous vertebroplasty: Technical considerations. J Vasc Interv Radiol. 2003;14:953
  17. Nakano M, Hirano N, Ishihara H, et al. Calcium phosphate cement leakage after percutaneous vertebroplasty for osteoporotic vertebral fractures: Risk factor analysis for cement leakage. J Neurosurg Spine. 2005;2:27
  18. Ryu KS, Park CK, Kim MC, et al. Dose-dependent epidural leakage of polymethylmethacrylate after percutaneous vertebroplasty in patients with osteoporotic vertebral compression fractures. J Neurosurg. 2002;96:56S
  19. Laredo JD, Hamze B. Complications of percutaneous vertebroplasty and their prevention. Skeletal Radiol. 2004;33:493
  20. Krebs J, Ferguson SJ, Bohner M, et al. Clinical measurements of cement injection pressure during vertebroplasty. Spine. 2005;30:118
  21. Yeom JS, Kim WJ, Choy WS, et al. Leakage of cement in percutaneous transpedicular vertebroplasty for painful osteoporotic compression fracture. J Bone Joint Surg Br. 2003;85:83
  22. Groen RJ, du Toit DF, Phillips FM, et al. Anatomical and pathological considerations in percutaneous vertebroplasty and kyphoplasty: A reappraisal of the vertebral venous system. Spine. 2004;29:1465
  23. Jensen ME, Evans AJ, Mathis JM, et al. Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: Technical aspects. AJNR Am J Neuroradiol. 1997;18:1897
  24. Cotton A, Dewater F, Cortet B, et al. Percutaneous vertebroplasty for osteolytic metastases and myeloma: Effects of percentage of lesions filling and leakage of methyl methacrylate at clinical follow-up. Radiology. 1996;200:525
  25. Bostrom MP, Lane JM. Future directions: Augmentation of osteoporotic vertebral bodies. Spine. 1997;22:38S
  26. Cyteval C, Sarrabere MP, Roux JO, et al. Acute osteoporotic vertebral collapse: Open study on percutaneous injection of acrylic surgical cement in 20 patients. Am J Radiol. 1999;173:1685
  27. Belkof SM, Mathis JM, Jasper LE, et al. The biomechanics of vertebroplasty. The effect of cement volume on mechanical behavior. Spine. 2001;14:1537
  28. Liebschner MAK, Rosenberg WS, Keaveny TM. Effects of bone cement volume and distribution of vertebral stiffness after vertebroplasty. Spine. 2001;14:1547
  29. Belkof SM, Mathis JM, Erbe EM, et al. Biomechanical evaluation of a new bone cement for use in vertebroplasty. Spine. 2000;25:1061
  30. Heini PF, Berlemann U, Kaufmann M, et al. Augmentation of mechanical properties in osteoporotic vertebral bones: A biomechanical investigation of vertebroplasty efficacy with different bone cements. Eur Spine J. 2001;10:164
  31. Tohmeh AG, Mathis JM, Fenton DC, et al. Biomechanical efficacy of unipedicular versus bipeducilar vertebroplasty for the management of osteoporotic compression fractures. Spine. 1999;24:1772
  32. Gaughen JR, Jensen ME, Schweickert PA, et al. Relevance of antecedent venography in percutaneous vertebroplasty for the treatment of osteoporotic compression fractures. Am J Neuroradiol. 2002;23:594
  33. Cortet B, Cotten A, Boutry N, et al. Percutaneous vertebroplasty in patients with osteolytic metastases or multiple myeloma. Rev Rhum Engl Ed. 1997;64:177
  34. Martin JB, Jean B, Sugiu K, et al. Vertebroplasty: Clinical experience and follow-up results. Bone. 1999;25:11S
  35. Weill A, Chiras J, Simon JM, et al. Spinal metastases: Indications for and results of percutaneous injection of acrylic surgical cement. Radiology. 1996;199:241
  36. Baroud G, Vant C, Giannitsios D, et al. Effect of vertebral shell on injection pressure and intravertebral pressure in vertebroplasty. Spine. 2004;30:68

PII: S0022-4804(10)00683-9

doi: 10.1016/j.jss.2010.08.006

Journal of Surgical Research
Volume 164, Issue 2 , Pages e253-e256 , December 2010