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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Transplantation of Cbfa1-Overexpressing Adipose Stem Cells Together With Vascularized Periosteal Flaps Repair Segmental Bone Defects
DOI: 10.1016/j.jss.2011.12.011
Background: Segmental bone defect is still a challenge to orthopedic surgeons. Currently available therapies for segmental bone defects have some drawbacks. Tissue engineering using pluripotent stem c...
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Jianjun Li,
Qun Zhao,
Enbo Wang,
Chuanhui Zhang,
Guangbin Wang,
Quan Yuan
et al.
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Full-length article
(In Press Uncorrected Proof)
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04 January 2012 |
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Overexpression of Programmed Death Ligand 1 in Dendritic Cells Inhibits Allogeneic Lymphocyte Activation in Mice
DOI: 10.1016/j.jss.2011.12.009
Background: Co-stimulatory molecules are pivotal for T cell activation. It is increasingly recognized that programmed death ligand 1 (PD-L1) is a novel co-stimulatory molecule, which raises the questi...
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Wenzhi Li,
Xiang Wang,
Renfu Chen,
Haitao Zhu,
Gang Chen,
Xiaoqing Sun
et al.
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Full-length article
(In Press Uncorrected Proof)
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03 January 2012 |
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Berberine Suppresses the TPA-Induced MMP-1 and MMP-9 Expressions Through the Inhibition of PKC-α in Breast Cancer Cells
DOI: 10.1016/j.jss.2011.11.1041
Background: Berberine (BBR) is one of the major alkaloids, and it has been reported to have a variety of pharmacologic effects, including inhibition of cell cycle progression. Here, we investigated th...
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Sangmin Kim,
Jeonghun Han,
Se Kyung Lee,
Min-Young Choi,
Jiyoung Kim,
Jeonghui Lee,
Seung Pil Jung,
Jee Soo Kim,
Jung-Han Kim,
Jun-Ho Choe,
Jeong Eon Lee,
Seok Jin Nam
et al.
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Full-length article
(In Press Uncorrected Proof)
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03 January 2012 |
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Erratum
DOI: 10.1016/j.jss.2011.12.004
In the March 2011 issue of the Journal of Surgical Research, we regret that in the article, “Trans-Iliac Rat Aorta Stenting: A Novel High Throughput Preclinical Stent Model for Restenosis and Thrombos...
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Erratum
(In Press Uncorrected Proof)
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26 December 2011 |
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Curcumin Protects Against Sepsis-Induced Acute Lung Injury in Rats
DOI: 10.1016/j.jss.2011.11.1032
The present study aimed to investigate the effect of curcumin on sepsis-induced acute lung injury (ALI) in rats, and explore its possible mechanisms. Male Sprague-Dawley rats were randomly divided int...
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Xuefei Xiao,
Mingshi Yang,
Dao Sun,
Shenghua Sun
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Full-length article
(In Press Uncorrected Proof)
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26 December 2011 |
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Effective Method to Remove Wound Bacteria: Comparison of Various Debridement Modalities in an In Vivo Porcine Model
DOI: 10.1016/j.jss.2011.11.1040
Background: Debridement is one of the crucial steps for successful wound care. In addition to removing necrotic tissue, debridement has been shown to reduce wound-associated bacteria that delay healin...
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Aron G. Nusbaum,
Joel Gil,
Marian K. Rippy,
J.B. Warne,
Jose Valdes,
Abel Claro,
Stephen C. Davis
et al.
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Full-length article
(In Press Uncorrected Proof)
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26 December 2011 |
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Hypercoagulability in Porcine Hemorrhagic Shock Is Present Early After Trauma and Resuscitation
DOI: 10.1016/j.jss.2011.12.001
Despite an increased awareness of the presence and impact of deep venous thrombosis (DVT) and pulmonary embolism (PE), they remain a major source of morbidity and mortality, especially in trauma patie...
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Saad Shebrain,
Elizabeth Steensma
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Discussion
(In Press Uncorrected Proof)
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23 December 2011 |
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Systems Biology Approach to Transplant Tolerance: Proof of Concept Experiments Using RNA Interference (RNAi) to Knock Down Hub Genes in Jurkat and HeLa Cells In Vitro1
DOI: 10.1016/j.jss.2011.12.002
Background: Systems biology is gaining importance in studying complex systems such as the functional interconnections of human genes. To investigate the molecular interactions involved in T cell immun...
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Wint Wah Lwin,
Ken Park,
Matthew Wauson,
Qin Gao,
David Perkins,
Ajai Khanna
et al.
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Full-length article
(In Press Uncorrected Proof)
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23 December 2011 |
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The Postoperative Serum Interleukin-15 Concentration Correlates with Organ Dysfunction and the Prognosis of Septic Patients Following Emergency Gastrointestinal Surgery
DOI: 10.1016/j.jss.2011.12.003
Objective: To clarify the time course of changes in the serum interleukin-15 (IL-15) concentrations in septic patients undergoing emergency surgery for abdominal infection and to investigate whether t...
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Akifumi Kimura,
Satoshi Ono,
Shuichi Hiraki,
Risa Takahata,
Hironori Tsujimoto,
Hiromi Miyazaki,
Manabu Kinoshita,
Kazuo Hatsuse,
Daizoh Saitoh,
Kazuo Hase,
Junji Yamamoto
et al.
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Full-length article
(In Press Uncorrected Proof)
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23 December 2011 |
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Do Primary Neuroendocrine Tumors and Metastasis Have the Same Characteristics?
DOI: 10.1016/j.jss.2011.11.1038
Background: Only one tumor site is usually biopsied to determine the histologic features of that patient’s entire tumor burden. We hypothesized that there are significant histologic and functional dif...
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Erika B. Lindholm,
John Lyons,
Catherine T. Anthony,
J Philip Boudreaux,
Yi-Zarn Wang,
Eugene A. Woltering
et al.
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Full-length article
(In Press Uncorrected Proof)
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23 December 2011 |
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NBD Peptides Protect Against Ischemia Reperfusion After Orthotopic Liver Transplantation in Rats
DOI: 10.1016/j.jss.2011.12.005
Background: NBD (NEMO binding domain) peptides could selectively inhibit the inflammation induced NF-κB activity, while sparing the protective functions of basal NF-κB activity. The aim of this study ...
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Ming-xiang Cheng,
Jian-ping Gong,
Yong Chen,
Zuo-jin Liu,
Bing Tu,
Chang-an Liu
et al.
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Full-length article
(In Press Uncorrected Proof)
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23 December 2011 |
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Progenitor Cell Mobilizing Treatments Prevent Experimental Transplant Arteriosclerosis
DOI: 10.1016/j.jss.2011.11.1014
Objective: Vascular rejection after organ transplantation is characterized by an arterial occlusive lesion, resulting from intimal proliferation occurring in response to arterial wall immune aggressio...
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Nicolas Roux,
Ebba Brakenhielm,
Caroline Freguin-Bouillant,
Françoise Lallemand,
Jean-Paul Henry,
Olivier Boyer,
Christian Thuillez,
Didier Plisonnier
et al.
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Full-length article
(In Press Uncorrected Proof)
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23 December 2011 |
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Projected Lifetime Risks and Hospital Care Expenditure for Traumatic Injury
DOI: 10.1016/j.jss.2011.11.1036
Dr. Chang and colleagues present risk and expenditure data for hospitalized trauma patients in California using the cumulative incidence estimate methodology. Their research is important in the contex...
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Hassan Tetteh
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Discussion
(In Press Uncorrected Proof)
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23 December 2011 |
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Phenacetin O-Deethylation is a Useful Tool for Evaluation of Hepatic Functional Reserve in Rats with CCl4-Induced Chronic Liver Injury
DOI: 10.1016/j.jss.2011.11.1037
Background: Mortality of liver resection is as high as 3.1% to 25% in patients with chronic liver disease. Evaluation of hepatic functional reserve is critical for the prediction of risk of postoperat...
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Zhe Liu,
Zengqiang Qu,
Xiaodong Li,
Meihua Cai,
Ping He,
Mi Zhou,
Jie Xiao,
Xiangrui Wang
et al.
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Full-length article
(In Press Uncorrected Proof)
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21 December 2011 |
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Curcumin for the Prevention of Acute Lung Injury in Sepsis: Is It More Than the Flavor of the Month?
DOI: 10.1016/j.jss.2011.11.1034
Curcumin is found in the popular spice turmeric, which is a member of the ginger family. It gives curry its bright yellow color and it is even used as a food color . It has been used for thousands of ...
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I. Michael Leitman
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Discussion
(In Press Uncorrected Proof)
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21 December 2011 |
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Are There Predictors of Malignancy in Patients with Multinodular Goiter?1
DOI: 10.1016/j.jss.2011.11.1035
Background: Multinodular goiters (MNG) have recently been shown to have an incidence of cancer that approaches that of solitary thyroid nodule. However, fine needle aspiration (FNA) of a MNG is limite...
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Jie Luo,
Catherine McManus,
Herbert Chen,
Rebecca S. Sippel
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Full-length article
(In Press Uncorrected Proof)
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21 December 2011 |
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Dynamics of Hepatic Gene Expression Profile in a Rat Cecal Ligation and Puncture Model
DOI: 10.1016/j.jss.2011.11.1031
Background: Sepsis remains a major clinical challenge in intensive care units. The difficulty in developing new and more effective treatments for sepsis exemplifies our incomplete understanding of the...
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Qian Yang,
John S.A. Mattick,
Mehmet A. Orman,
Tung T. Nguyen,
Marianthi G. Ierapetritou,
Francois Berthiaume,
Ioannis P. Androulakis
et al.
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Full-length article
(In Press Uncorrected Proof)
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19 December 2011 |
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Bromelain Ameliorates the Wound Microenvironment and Improves the Healing of Firearm Wounds
DOI: 10.1016/j.jss.2011.11.1027
Background: In a previous study, we proposed a new therapy using topical bromelain as a supplement to simple wound-track incision for the debridement of firearm wounds. This enzymatic debridement grea...
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Si-Yu Wu,
Wei Hu,
Bo Zhang,
Shuai Liu,
Jian-Min Wang,
Ai-Min Wang
et al.
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Full-length article
(In Press Uncorrected Proof)
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19 December 2011 |
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Damage Control Resuscitation Decreases Systemic Inflammation After Hemorrhage
DOI: 10.1016/j.jss.2011.11.1028
Background: Severe hemorrhagic shock and resuscitation initiates a dysfunctional systemic inflammatory response leading to end-organ injury. Clinical evidence supports the transfusion of high ratios o...
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Amy T. Makley,
Michael D. Goodman,
Ritha M. Belizaire,
Lou Ann W. Friend,
Jay A. Johannigman,
Warren C. Dorlac,
Alex B. Lentsch,
Timothy A. Pritts
et al.
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Full-length article
(In Press Uncorrected Proof)
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19 December 2011 |
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Biologic Scaffold Remodeling in a Dog Model of Complex Musculoskeletal Injury
DOI: 10.1016/j.jss.2011.11.1029
Background: Current treatment principles for muscle injuries with volumetric loss have been largely derived from empirical observations. Differences in severity or anatomic location have determinant e...
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Neill J. Turner,
John S. Badylak,
Douglas J. Weber,
Stephen F. Badylak
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Full-length article
(In Press Uncorrected Proof)
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19 December 2011 |
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Gender Differences at the Cellular Level
DOI: 10.1016/j.jss.2011.11.1023
In a paper recently published in the Journal of Surgical Research, Drs. Hogg et al. from the Kibbe laboratory provide a report describing the putative interaction between nitric oxide (NO) therapy and...
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Robert Allen,
Luke Packard Brewster
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Discussion
(In Press Uncorrected Proof)
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16 December 2011 |
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TGF-α Equalizes Age Disparities in Stem Cell-Mediated Cardioprotection
DOI: 10.1016/j.jss.2011.11.1012
Background: Neonatal mesenchymal stem cells exhibit less cardioprotective potential than their adult counterparts. Transforming growth factor-α (TGF-α) has been shown to stimulate adult stem cell VEGF...
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Jeremy L. Herrmann,
Jeremy W. Fiege,
Aaron M. Abarbanell,
Brent R. Weil,
Yue Wang,
Jeffrey A. Poynter,
Mariuxi C. Manukyan,
Benjamin D. Brewster,
Daniel R. Meldrum
et al.
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Full-length article
(In Press Uncorrected Proof)
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16 December 2011 |
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Impact of Age on Liver Regeneration Response to Injury After Partial Hepatectomy in a Rat Model
DOI: 10.1016/j.jss.2011.11.1022
Background: Liver resection is a feasible treatment for multiple liver diseases. There is no evidence about the impact of age on liver regeneration. Objective: To assess the effect of age on liver reg...
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Juan Manuel Sánchez-Hidalgo,
Álvaro Naranjo,
Rubén Ciria,
Isidora Ranchal,
Patricia Aguilar-Melero,
Gustavo Ferrín,
Amparo Valverde,
Sebastián Rufián,
Pedro López-Cillero,
Jordi Muntané,
Javier Briceño
et al.
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Full-length article
(In Press Uncorrected Proof)
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16 December 2011 |
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Increased JNK in Males Compared with Females in a Rodent Model of Abdominal Aortic Aneurysm
DOI: 10.1016/j.jss.2011.11.1024
Background: In humans, there is a 4:1 male:female ratio in the incidence of abdominal aortic aneurysms (AAAs). c-Jun-N-terminal kinase (JNK) is an important upstream regulator of several enzymes invol...
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Paul D. DiMusto,
Guanyi Lu,
Abhijit Ghosh,
Karen J. Roelofs,
Omar Sadiq,
Brendan McEvoy,
Gang Su,
Adriana Laser,
Castigliano M. Bhamidipati,
Gorav Ailawadi,
Peter K. Henke,
Jonathan L. Eliason,
Gilbert R. Upchurch
et al.
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Full-length article
(In Press Uncorrected Proof)
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16 December 2011 |
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Effective Oncolytic Vaccinia Therapy for Human Sarcomas
DOI: 10.1016/j.jss.2011.11.1030
Background: Approximately one fourth of bone and soft-tissue sarcomas recur after prior treatment. GLV-1h68 is a recombinant, replication-competent vaccinia virus that has been shown to have oncolytic...
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Shuangba He,
Pingdong Li,
Chun-Hao Chen,
Richard L. Bakst,
Natalya Chernichenko,
Yong A. Yu,
Nanhai Chen,
Aladar A. Szalay,
Zhenkun Yu,
Yuman Fong,
Richard J. Wong
et al.
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Full-length article
(In Press Uncorrected Proof)
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16 December 2011 |
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Regeneration: Letting the Scaffold do the Work
DOI: 10.1016/j.jss.2011.11.1026
Barakat et al,. in a paper recently published in the Journal of Surgical Research, report on the development of a humanized liver segment from a decellularized porcine liver by seeding the “liver” wit...
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Aaron M. Rosado,
Luke Packard Brewster
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Discussion
(In Press Uncorrected Proof)
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15 December 2011 |
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Effects of Thyroid Hormone Supplementation on Anastomotic Healing After Segmental Colonic Resection
DOI: 10.1016/j.jss.2011.11.1015
Background: Alterations of thyroid hormones in colorectal surgery were previously studied. The aim of the present study was to determine the effects of triiodothyronine (T3) supplementation on anastom...
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Kerem Karaman,
Erdal Birol Bostanci,
Nazmiye Dincer,
Murat Ulas,
Ilter Ozer,
Tahsin Dalgic,
Ugur Ercin,
Ayse Bilgihan,
Zeynep Ginis,
Musa Akoglu
et al.
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Full-length article
(In Press Uncorrected Proof)
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15 December 2011 |
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The Association of Manganese Superoxide Dismutase Expression in Barrett's Esophageal Progression With MnTBAP and Curcumin Oil Therapy
DOI: 10.1016/j.jss.2011.11.1013
Background: The aim of this study was to investigate the relationship between reflux induced bile insult and MnSOD expression, as well as to examine therapies to preserve MnSOD expression. Additionall...
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Suzanne C. Schiffman,
Yan Li,
Robert C.G. Martin
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Full-length article
(In Press Uncorrected Proof)
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15 December 2011 |
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Tensile Strength of Biological Fibrin Sealants: A Comparative Study
DOI: 10.1016/j.jss.2011.11.1017
Background: Fibrin sealants are commonly used in liver surgery, although their effectiveness in routine clinical practice remains controversial. Individual sealant characteristics are based on hemosta...
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Laurence Lacaze,
Nicolas Le Dem,
Michael Bubenheim,
Basile Tsilividis,
Julien Mezghani,
Lilian Schwartz,
Arnaud Francois,
Jean Yves Ertaud,
Maurice Bagot d'Arc,
Michel Scotté
et al.
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Full-length article
(In Press Uncorrected Proof)
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15 December 2011 |
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Modified Map-Seeking Circuit: Use of Computer-Aided Detection in Locating Postoperative Retained Foreign Bodies1
DOI: 10.1016/j.jss.2011.11.1018
Background: More than 98% of intra-operative X-rays taken to search for postoperative retained foreign bodies (RFBs) have negative findings; in over 30% of cases of such X-rays, the finding is a false...
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Bolanle Asiyanbola,
Chao Cheng-Wu,
Richard Schulick,
Jonathan S. Lewin,
Ralph Etienne-Cummings
et al.
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Full-length article
(In Press Uncorrected Proof)
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15 December 2011 |
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Working Towards a Better Understanding of the Biomechanics of the Carotid Artery
DOI: 10.1016/j.jss.2011.11.1016
Perhaps no other arterial bed and its management have been as intensely studied as the carotid artery. Whether to patch or not following carotid endarterectomy (CEA), what type of patch to use, compli...
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Robert Alan McCready
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Discussion
(In Press Uncorrected Proof)
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12 December 2011 |
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Immunocompetent Orthotopic Pancreatic Cancer Murine Model: A Step in the Right Direction
DOI: 10.1016/j.jss.2011.11.1011
Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Despite recent advances in the modern care of this recalcitrant disease, survival rate remains dismal . In ...
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Quyen D. Chu,
Roger H. Kim
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Discussion
(In Press Corrected Proof)
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02 December 2011 |
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Germline Mutations in SMAD4 Disrupt Bone Morphogenetic Protein Signaling
DOI: 10.1016/j.jss.2011.11.008
Introduction: Juvenile polyposis (JP) is an autosomal dominant disease that predisposes to GI malignancies. Germline mutations in the tumor suppressor gene SMAD4 account for approximately 20% of JP ca...
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Jennifer C. Carr,
Fadi S. Dahdaleh,
Donghong Wang,
James R. Howe
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Full-length article
(In Press Uncorrected Proof)
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02 December 2011 |
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Clinical Significance of Serum Soluble E-cadherin in Colorectal Carcinoma1
DOI: 10.1016/j.jss.2011.11.009
Background: E-cadherin expression has been associated with an outcome in patients with colorectal cancer, and serum levels of soluble E-cadherin (sE-cadherin) are significantly elevated in patients wi...
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Yoshinaga Okugawa,
Yuji Toiyama,
Yasuhiro Inoue,
Takashi Iwata,
Hiroyuki Fujikawa,
Susumu Saigusa,
Naomi Konishi,
Koji Tanaka,
Keiichi Uchida,
Masato Kusunoki
et al.
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Full-length article
(In Press Corrected Proof)
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02 December 2011 |
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Remodeling of Extracellular Matrix Patch used for Carotid Artery Repair
DOI: 10.1016/j.jss.2011.11.001
Background: We evaluated the in vitro strength and in vivo arterial-wall response to an extracellular-matrix-based patch material in a sheep model of carotid artery repair. Materials and Methods: A si...
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Anna Fallon,
Traci Goodchild,
Ruoya Wang,
Robert G. Matheny
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Full-length article
(In Press Uncorrected Proof)
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28 November 2011 |
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Protective Effects of Melatonin and S-Methylisothiourea on Mechlorethamine Induced Nephrotoxicity
DOI: 10.1016/j.jss.2011.11.002
Background: In this study, we aimed to investigate the protective effects of melatonin (MEL) and S-methylisothiourea (SMT) on mechlorethamine (MEC) induced nephrotoxicity. Materials and Methods: A tot...
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Zeki Ilker Kunak,
Enis Macit,
Hakan Yaren,
Halil Yaman,
Erdinc Cakir,
Ibrahim Aydin,
Turker Turker,
Yasemin Gulcan Kurt,
Ayhan Ozcan,
Bulent Uysal,
Salim Isbilir,
Emin Ozgur Akgul,
Tuncer Cayci,
Ahmet Korkmaz,
Levent Kenar
et al.
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Full-length article
(In Press Corrected Proof)
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28 November 2011 |
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Functional Analysis of Alloreactive Memory CD4+ T Cells Derived from Skin Transplantation Recipient and Naïve CD4+ T Cells Derived from Untreated Mice
DOI: 10.1016/j.jss.2011.11.003
Background: Memory T cells (TMs) exhibit differential susceptibility to many immunomodulatory strategies that induce immunologic tolerance in naïve T cells, which are believed to be an important barri...
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Lei Luo,
Chengwen Li,
Wenqiao Wu,
Jun Lu,
Yanni Zhou,
Juan Shan,
Shengfu Li,
Dan Long,
Yingjia Guo,
Youping Li,
Li Feng
et al.
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Full-length article
(In Press Corrected Proof)
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28 November 2011 |
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Berberine Inhibits Lipopolysaccharide- and Polyethylene Particle-Induced Mouse Calvarial Osteolysis In Vivo
DOI: 10.1016/j.jss.2011.11.004
Background: Wear particle-induced osteolysis could lead to the aseptic loosening of implants. Studies have suggested that endotoxins, such as lipopolysaccharides (LPS), may be the primary causes of we...
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Xiaoxiao Zhou,
Chao Zhang,
Xiaoqing Wang,
Bingchen An,
Peng Zhang,
Zhen’an Zhu
et al.
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Full-length article
(In Press Corrected Proof)
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24 November 2011 |
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Activation of Cholinergic Anti-Inflammatory Pathway Contributes to the Protective Effects of 100% Oxygen Inhalation on Zymosan-Induced Generalized Inflammation in Mice
DOI: 10.1016/j.jss.2011.10.037
Background: The 100% oxygen inhalation has been demonstrated to have a protective effect on mice with zymosan-induced generalized inflammation. However, the underlying mechanism is largely unknown. Th...
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Zishen Zhang,
Xiaoguang Bai,
Kejun Du,
Yi Huang,
Wenyong Wang,
Yiling Zhao,
Yuping Pei,
Jinglan Mu,
Han Han,
Sheng Hu,
Shuzhi Li,
Hailong Dong,
Yan Lu,
Lichao Hou,
Lize Xiong
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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Blockade of Chloride Ion Transport Enhances the Cytocidal Effect of Hypotonic Solution in Gastric Cancer Cells
DOI: 10.1016/j.jss.2011.10.039
Background: Cancer cells that are exfoliated into the peritoneal cavity during surgery are viable and have the potential to produce peritoneal recurrence. Although peritoneal lavage with distilled wat...
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Daisuke Iitaka,
Atsushi Shiozaki,
Daisuke Ichikawa,
Toshiyuki Kosuga,
Shuhei Komatsu,
Kazuma Okamoto,
Hitoshi Fujiwara,
Hiromichi Ishii,
Takashi Nakahari,
Yoshinori Marunaka,
Eigo Otsuji
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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Histologic and Biomechanical Evaluation of Biologic Meshes following Colonization with Pseudomonas aeruginosa
DOI: 10.1016/j.jss.2011.10.044
Background: Biologic meshes have become increasingly popular for the repair of abdominal wall defects, especially in contaminated sites. The purpose of this study was to evaluate the histologic and bi...
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Charles F. Bellows,
Ben Wheatley,
Krzysztof Moroz,
Stephanie Rosales,
Lisa A. Morici
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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PKI-587 and Sorafenib Targeting PI3K/AKT/mTOR and Ras/Raf/MAPK Pathways Synergistically Inhibit HCC Cell Proliferation
DOI: 10.1016/j.jss.2011.10.045
Background: Deregulated Ras/Raf/MAPK and PI3K/AKT/mTOR signaling pathways are found in hepatocellular carcinoma (HCC). This study aimed to test the inhibitory effects of PKI-587 and sorafenib as singl...
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Roberto Gedaly,
Paul Angulo,
Jonathan Hundley,
Michael F. Daily,
Changguo Chen,
B. Mark Evers
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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Ultrasound Visualization of the Spinal Accessory Nerve In Vivo1
DOI: 10.1016/j.jss.2011.10.046
Background: Inadvertent injury of the spinal accessory nerve during surgical procedures is a cause of significant morbidity with medicolegal repercussions. Surface anatomy is an unreliable guide to th...
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Seyed A. Mirjalili,
Jill C. Muirhead,
Mark D. Stringer
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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Individualizing Care for Locoregional Pancreatic Cancer?
DOI: 10.1016/j.jss.2011.10.041
Surgical resection remains the only curative option for patients with early stage pancreatic cancer, with 5-y survival rates ranging from 10%–35% depending on the time period and receipt of adjuvant o...
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Taylor S. Riall,
Kimberly M. Brown
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Discussion
(In Press Corrected Proof)
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21 November 2011 |
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Early Activation of the Inflammatory Response in the Liver of Brain-Dead Non-Human Primates
DOI: 10.1016/j.jss.2011.10.042
Background: Donor brain death (BD) triggers a systemic inflammatory response that reduces organ quality and increases immunogenicity of the graft. We characterized the early innate immune response ind...
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Juan Sebastian Danobeitia,
Jamie M. Sperger,
Matthew S. Hanson,
Elisa E. Park,
Peter J. Chlebeck,
Drew A. Roenneburg,
Mallory L. Sears,
Jolien X. Connor,
Alice Schwarznau,
Luis A. Fernandez
et al.
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Full-length article
(In Press Uncorrected Proof)
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21 November 2011 |
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Mucolysis by Ascorbic Acid and Hydrogen Peroxide on Compact Mucin Secreted in Pseudomyxoma Peritonei
DOI: 10.1016/j.jss.2011.10.038
Background: This study examines the potential efficacy of hydrogen peroxide and ascorbic acid in the dissolution of mucinous ascites from pseudomyxoma peritonei. Methods: The mucolytic action of both ...
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Krishna Pillai,
Javed Akhter,
Terence C. Chua,
David L. Morris
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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Fluorescence Diagnosis of Metastatic Lymph Nodes Using 5-Aminolevulinic Acid (5-ALA) in a Mouse Model of Colon Cancer
DOI: 10.1016/j.jss.2011.10.031
Background: Lymph node metastasis is one of the most critical prognostic factors in patients with colorectal cancer. Although regional lymph nodes should be surgically resected and pathologically exam...
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Shigeru Kato,
Junichiro Kawamura,
Kenji Kawada,
Suguru Hasegawa,
Yoshiharu Sakai
et al.
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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The Impact of Trauma Admissions in the Elderly
DOI: 10.1016/j.jss.2011.10.043
Elderly patients may decrease their work and physical activities as they get older. Do they require more frequent hospital admission following trauma? Is this due to underlying co-morbid conditions, r...
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I. Michael Leitman
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Discussion
(In Press Corrected Proof)
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21 November 2011 |
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Antioxidant Effects of Propofol on Tourniquet-Induced Ischemia-Reperfusion Injury: An Experimental Study
DOI: 10.1016/j.jss.2011.10.032
Purpose: This experimental study aimed to investigate the antioxidant effects of propofol anesthesia at induction doses in a rat skeletal muscle ischemia/reperfusion injury model. Methods: Twenty-six ...
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Fatih Ozkan,
Yeşim Şenayli,
Huseyin Ozyurt,
Unal Erkorkmaz,
Bora Bostan
et al.
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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Carotid Artery Stenting (CAS)—The Unwritten Chapter
DOI: 10.1016/j.jss.2011.10.053
CAS has garnered considerable enthusiasm among interventionalists and especially nonsurgical interventionalists as a “non-inferior” alternative to carotid endarterectomy (CEA). Indeed, the widely anti...
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Robert Alan McCready
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Discussion
(In Press Corrected Proof)
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21 November 2011 |
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Elderly Recipients of Hepatitis C Positive Renal Allografts Can Quickly Develop Liver Disease
DOI: 10.1016/j.jss.2011.10.028
Our institution explored using allografts from donors with Hepatitis C virus (HCV) for elderly renal transplantation (RT). Thirteen HCV– elderly recipients were transplanted with HCV+ allografts (eD+/...
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Tanya R. Flohr,
Hugo Bonatti,
Tjasa Hranjec,
Doug S. Keith,
Peter I. Lobo,
Sean C. Kumer,
Timothy M. Schmitt,
Robert G. Sawyer,
Timothy L. Pruett,
John P. Roberts,
Kenneth L. Brayman
et al.
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Full-length article
(In Press Uncorrected Proof)
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21 November 2011 |
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Rapamycin Induces Heme Oxygenase-1 in Liver but Inhibits Bile Flow Recovery after Ischemia
DOI: 10.1016/j.jss.2011.10.033
Background/Aims: Rapamycin, which is employed in the management of patients undergoing liver surgery, induces the synthesis of heme oxygenase-1 (HO-1) in some non-liver cell types. The aim was to inve...
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Alwine Kist,
Joris Wakkie,
Max Madu,
Ruth Versteeg,
Judith ten Berge,
Andrej Nikolic,
Vincent B. Nieuwenhuijs,
Robert J. Porte,
Robert T.A. Padbury,
Greg J. Barritt
et al.
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Full-length article
(In Press Uncorrected Proof)
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21 November 2011 |
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A Technique of Recipient Portal Venoplasty and Cuff Insertion for Portal Revascularization in Orthotopic Rat Liver Transplantation
DOI: 10.1016/j.jss.2011.10.047
Rat orthotopic liver transplantation (ROLT) remains one of the most challenging animal procedures, requiring significant technical expertise and practice. In a paper recently published in the Journal ...
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Christopher W. Macomber,
Shimul A. Shah
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Discussion
(In Press Uncorrected Proof)
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21 November 2011 |
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Gastric Emptying is Delayed in Transgastric Notes: A Randomized Study in Swine
DOI: 10.1016/j.jss.2011.10.034
Aim: The aim of this study was to evaluate the restoration of gastrointestinal motility after NOTES using capsule endoscopy (CE). Materials and Methods: Twenty adult Yorkshire pigs were randomly assig...
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Henry Córdova,
Carlos Guarner-Argente,
Graciela Martínez-Pallí,
Ricard Navarro,
Antonio Rodríguez-D'Jesús,
Cristina Rodríguez de Miguel,
Mireia Beltrán,
M. Àngels Martínez-Zamora,
Jaume Comas,
Antonio M. Lacy,
Christopher C. Thompson,
Gloria Fernández-Esparrach
et al.
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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Understanding the Brain-Heart Axis in Neurological Trauma
DOI: 10.1016/j.jss.2011.10.040
The cardiovascular physiologic effects of traumatic brain injury remain only partially understood. The autoregulatory manifestations of closed head injury have long been considered to be a catecholami...
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I. Michael Leitman
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Discussion
(In Press Corrected Proof)
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21 November 2011 |
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The Effect of Remnant Preservation on Patterns of Gene Expression in a Rabbit Model of Anterior Cruciate Ligament Reconstruction
DOI: 10.1016/j.jss.2011.10.035
Background: Anterior cruciate ligament (ACL) reconstruction with remnant preservation technique had been thought to be a more favorable milieu for graft reinnervation, revascularization, and ligamenti...
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Guo ming Xie,
Xiao qiao Huang fu,
Jin zhong Zhao
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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Curcumin Protects Against Ischemia/Reperfusion Injury in Rat Skeletal Muscle
DOI: 10.1016/j.jss.2011.11.006
The body of literature describing preventative modalities against ischemia reperfusion injury (IRI) seems to be expanding with the ferocity of the oxidative burst that it seeks to ablate. This is clea...
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Jonathan Bank,
David H. Song
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Discussion
(In Press Corrected Proof)
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21 November 2011 |
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Use of a Modified Chitosan–Dextran Gel to Prevent Peritoneal Adhesions in a Porcine Hemicolectomy Model
DOI: 10.1016/j.jss.2011.10.029
Background: The prevention of peritoneal adhesions following abdominal surgery remains an ongoing challenge, with the ideal product for adhesion reduction still elusive. This study examines the outcom...
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Chris I.W. Lauder,
Andrew Strickland,
Guy J. Maddern
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Full-length article
(In Press Corrected Proof)
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18 November 2011 |
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Human Isolates of Cronobacter sakazakii Bind Efficiently to Intestinal Epithelial Cells In Vitro to Induce Monolayer Permeability and Apoptosis
DOI: 10.1016/j.jss.2011.10.030
Background: Cronobacter sakazakii (CS) is an emerging opportunistic pathogen that causes life-threatening infections in infants. This pathogen has been implicated in the outbreaks of necrotizing enter...
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Quin Liu,
Rahul Mittal,
Claudia N. Emami,
Carol Iversen,
Henri R. Ford,
Nemani V. Prasadarao
et al.
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Full-length article
(In Press Corrected Proof)
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16 November 2011 |
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Projected Lifetime Risks and Hospital Care Expenditure for Traumatic Injury
DOI: 10.1016/j.jss.2011.10.022
Background: The lifetime risk and expected cost of trauma care would be valuable for health policy planners, but this information is currently unavailable. The cumulative incidence rates methodology, ...
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David C. Chang,
Jamie E. Anderson,
Leslie Kobayashi,
Raul Coimbra,
Stephen W. Bickler
et al.
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Full-length article
(In Press Corrected Proof)
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16 November 2011 |
