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A pivotal role of phospholipase A2 (PLA2) and platelet-activating factor-acetylhydrolase (PAF-AcH) as enzymes involved in lung inflammation has recently been suggested. The objective of this study was to elucidate the role and the time dependence of PLA2 and PAF-AcH fluctuations in the lung relative to the evolution of intestinal ischemia-reperfusion (IIR).