Abstract
Introduction
Global burn injury burden disproportionately impacts low- and middle-income countries.
Surgery is a mainstay of burn treatment, yet access to surgical care appears to be
inequitably distributed for women. This study sought to identify gender disparities
in mortality and access to surgery for burn patients in the World Health Organization
Global Burn Registry (GBR).
Methods
We queried the World Health Organization GBR for a retrospective cohort (2016-2021).
Patients were stratified by sex. Outcomes of interest were in-hospital mortality and
surgical treatment. Patient demographics, injury characteristics, outcomes, and health
facility resources were compared between sexes with Wilcoxon rank sum test for nonparametric
medians, and chi-squared or Fisher’s exact test for nonparametric proportions. Multivariable
logistic regressions were performed to assess the relationships between sex and mortality,
and sex and surgery.
Results
Of 8445 patients in the GBR from 20 countries (10 low resource), 40% of patients were
female, with 51% of all patients receiving surgical treatment during their hospitalization.
Female patients had a higher incidence of mortality (24% versus 15%, P < 0.001) and a higher median total body surface area (20% versus 15%, P < 0.001), yet a lower incidence of surgery (47% versus 53%, P < 0.001) following burn injury when compared to males. In multivariable analysis,
female sex was independently associated with mortality after controlling for age,
time to presentation, smoke injury, percent total body surface area, surgery, and
country income status. Female sex was independently associated with surgical care
(odds ratio 0.86, P = 0.001).
Conclusions
Female burn patients suffer higher mortality compared to males and are less likely
to receive surgery. Further study into this gender disparity in burns is warranted.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of Surgical ResearchAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Epidemiology of burns throughout the world. Part I: distribution and risk factors.Burns. 2011; 37: 1087-1100
- Recent trends in burn epidemiology worldwide: a systematic review.Burns. 2017; 43: 249-257
- Biofilm and a new appraisal of burn wound sepsis.Burns. 2010; 36: 49-56
- Gender differences in burns: a study from emergency centres in the Western Cape, South Africa.Burns. 2016; 42: 1600-1608
- Barriers to accessing surgical care: a cross-sectional survey conducted at a tertiary care hospital in Karachi, Pakistan.World J Surg. 2013; 37: 2313-2321
- Inequitable Access to timely cleft palate surgery in low- and middle-income countries.World J Surg. 2016; 40: 1047-1052
- The design and evaluation of a system for improved surveillance and prevention programmes in resource-limited settings using a hospital-based burn injury questionnaire.Inj Prev. 2016; 22: i56-i62
- The 17 goals | sustainable development.(Available at:)https://sdgs.un.org/goalsDate accessed: February 20, 2022
- Global burn registry FAQs. global burn registry.(Available at:)https://www.who.int/teams/social-determinants-of-health/safety-and-mobility/burns/global-burn-registryDate accessed: February 14, 2022
- Gender-based disparities in burn injuries, care and outcomes: a World Health Organization (WHO) Global Burn Registry cohort study.Am J Surg. 2022; 223: 157-163
- Global burn Registry perspective on head and neck burns.Ann Plast Surg. 2020; 87: 33-38
- An analysis of factors associated with burn injury outcomes in low- and middle-income countries.J Surg Res. 2021; 257: 442-448
- The global burn Registry: a work in progress.J Burn Care Res. 2020; 41: 929-934
- Management of burn wounds.Eur J Pediatr Surg. 2013; 23: 341-348
- Important developments in burn care.Plast Reconstr Surg. 2017; 139: 120e-138e
- Meta-analysis of early excision of burns.Burns. 2006; 32: 145-150
- Gender-related differences in care-seeking behaviour for newborns: a systematic review of the evidence in South Asia.BMJ Glob Health. 2019; 4e001309
- Gender differences in care-seeking behavior and healthcare consumption immediately after whiplash trauma.PLoS One. 2017; 12e0176328
- Gender differences in factors associated with the total delay in treatment of pulmonary tuberculosis patients: a cross-sectional study in selangor, Malaysia.Int J Environ Res Public Health. 2022; 19: 6258-6273
- Gender equality and global health: intersecting political challenges.J Glob Health. 2020; 10010701
- Burn injury Fact Sheet. American Burn Association National Burn Repository, Chicago, IL2016
- Sex-based differences in inpatient burn mortality.World J Surg. 2019; 43: 3035-3043
- National trends in burn and inhalation injury in burn patients: results of analysis of the nationwide inpatient sample database.J Burn Care Res. 2015; 36: 258-265
- Increased mortality in women: sex differences in burn outcomes.Burns Trauma. 2017; 5: 18-26
- National burn Repository 2016 report, v.12.0. American Burn Association, Chicago, IL2016
Article info
Publication history
Published online: November 23, 2022
Accepted:
October 17,
2022
Received in revised form:
October 2,
2022
Received:
March 1,
2022
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.