Abstract
Introduction
Early initiation of chemotherapy after surgery for colon cancer has survival benefits.
Immediate adjuvant chemotherapy (IAC) involves giving chemotherapy during surgical
resection and immediately postoperatively. This novel approach has been shown to be
safe, eliminating delays in adjuvant treatment that could increase the risk of micro-metastatic
spread. The aim of this study was to assess the willingness of the general public
to accept IAC.
Materials and methods
Between March and April 2021, 800 telephone interviews were conducted with a sample
of adult New York State residents. The Survey Research Institute of Cornell University
conducted all surveys. Kruskal–Wallis, chi-squared, and Fisher’s tests were conducted
using R 4.0.2.
Results
Three scenarios were presented: (1) receiving IAC resulting in improved survival and
quality of life, (2) finishing chemotherapy earlier without survival impact, and (3)
finishing chemotherapy earlier but with possible side effects. Respondents with higher
education were more likely to accept (1) & (2), males were more likely to accept (2)
& (3), higher income respondents were more likely to accept (1) & (3), and those with
more work hours were more likely to accept (2). Lastly, 16% responded they would be
very or extremely likely, and 52% respondents would be somewhat likely or likely to
accept intraoperative chemotherapy, even if it may not be necessary.
Conclusions
Respondents were likely to accept IAC if offered. Given the known risk of delayed
adjuvant chemotherapy (AC) in colon cancer, further research is warranted to determine
the survival and quality of life (QOL) benefits of IAC.
Keywords
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Article info
Publication history
Published online: November 28, 2022
Accepted:
November 6,
2022
Received in revised form:
October 19,
2022
Received:
March 1,
2022
Identification
Copyright
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