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  • Shock/sepsis/trauma/critical care

    Effects of glycine, pyruvate, resveratrol, and nitrite on tissue injury and cytokine response in endotoxemic rats

    Journal of Surgical Research
    Vol. 183Issue 1e7–e21Published online: February 11, 2013
    • Tim Hamburger
    • Martina Broecker-Preuss
    • Matthias Hartmann
    • F. Ulrich Schade
    • Herbert de Groot
    • Frank Petrat
    Cited in Scopus: 24
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      Glycine, pyruvate, resveratrol, and nitrite are well-known protective compounds among others in ischemic tissue injury. Here, we compared their effects in acute lipopolysaccharide (LPS)-induced shock in rats to assess whether inhibition of the proinflammatory cytokine response is a prerequisite for their protective actions.
      Effects of glycine, pyruvate, resveratrol, and nitrite on tissue injury and cytokine response in endotoxemic rats
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