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  • Shock/Sepsis/Trauma/Critical Care

    Pretreatment of Rho Kinase Inhibitor Inhibits Systemic Inflammation and Prevents Endotoxin-Induced Acute Lung Injury in Mice

    Journal of Surgical Research
    Vol. 171Issue 2e209–e214Published online: September 5, 2011
    • Ren Yu Ding
    • Dong Mei Zhao
    • Zhi Dan Zhang
    • Ren Xuan Guo
    • Xiao Chun Ma
    Cited in Scopus: 28
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      Systemic inflammatory mediators play an important role in the development of sepsis. In this study, we analyzed the role of Rho kinase in the activation of immune response and acute lung injury in a mouse model of sepsis.
      Pretreatment of Rho Kinase Inhibitor Inhibits Systemic Inflammation and Prevents Endotoxin-Induced Acute Lung Injury in Mice
    • Shock/Sepsis/Trauma/Critical Care

      Hydrogen-Rich Saline Provides Protection Against Hyperoxic Lung Injury

      Journal of Surgical Research
      Vol. 165Issue 1e43–e49Published online: October 18, 2010
      • Qiang Sun
      • Jianmei Cai
      • Shulin Liu
      • Yun Liu
      • Weigang Xu
      • Hengyi Tao
      • and others
      Cited in Scopus: 55
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        Hydrogen has been proven to be a novel antioxidant through its selectively reducing of the hydroxyl radical. In this study, we investigated the effects of hydrogen-rich saline on the prevention of acute lung injury induced by hyperoxia (HALI) in rats.
        Hydrogen-Rich Saline Provides Protection Against Hyperoxic Lung Injury
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